帕金森病患者的复杂任务表现评估（CTPA）与功能性认知
Complex Task Performance Assessment (CTPA) and Functional Cognition in People With Parkinson's Disease.
作者信息
Davis Alison, Wolf Timothy J, Foster Erin R
机构信息
Alison Davis, OTD, is Occupational Therapist, Barnes-Jewish Hospital, St. Louis, MO.
Timothy J. Wolf, PhD, OTD, is Associate Professor and Department Chair, Department of Occupational Therapy, School of Health Professions, University of Missouri, Columbia.
出版信息
Am J Occup Ther. 2019 Sep/Oct;73(5):7305205060p1-7305205060p9. doi: 10.5014/ajot.2019.031492.
OBJECTIVE
The objective of this study was to determine how Parkinson's disease (PD) affects functional cognition as assessed by the Complex Task Performance Assessment (CTPA) and to examine the associations of CTPA performance with other indicators of executive function in people with PD.
METHOD
Volunteers with PD without dementia (n = 20) and community control participants (n = 19) completed neuropsychological testing, patient-reported outcome measures, and the CTPA.
RESULTS
There were no group differences for CTPA performance accuracy; however, the PD group took longer to complete the CTPA than did the control group. In the PD group, inefficient CTPA performance correlated with poorer cognitive flexibility and worse reported everyday shifting and task monitoring.
CONCLUSION
Decreased executive function, namely cognitive flexibility and attentional control, may impair functional cognition in people with PD. Future studies with larger, more diverse samples are warranted to determine the discriminant validity and sensitivity of the CTPA. Use of performance-based assessments such as the CTPA may increase the understanding of functional cognition in people with PD.
目的
本研究的目的是确定帕金森病（PD）如何影响通过复杂任务表现评估（CTPA）所评估的功能认知，并研究CTPA表现与PD患者其他执行功能指标之间的关联。
方法
无痴呆的PD志愿者（n = 20）和社区对照参与者（n = 19）完成了神经心理学测试、患者报告的结局指标以及CTPA。
结果
CTPA表现准确性方面无组间差异；然而，PD组完成CTPA的时间比对照组更长。在PD组中，CTPA表现低效与较差的认知灵活性以及较差的日常转换和任务监控报告相关。
结论
执行功能下降，即认知灵活性和注意力控制下降，可能会损害PD患者的功能认知。有必要开展样本量更大、更多样化的未来研究，以确定CTPA的区分效度和敏感性。使用如CTPA这样基于表现的评估可能会增进对PD患者功能认知的理解。
Zotero 插件