Cognitive Neurology and Alzheimer's Disease Center, Northwestern Feinberg School of Medicine, Chicago, IL, USA.
Neurology. 2013 Mar 12;80(11 Suppl 3):S54-64. doi: 10.1212/WNL.0b013e3182872ded.
Cognition is 1 of 4 domains measured by the NIH Toolbox for the Assessment of Neurological and Behavioral Function (NIH-TB), and complements modules testing motor function, sensation, and emotion. On the basis of expert panels, the cognition subdomains identified as most important for health, success in school and work, and independence in daily functioning were Executive Function, Episodic Memory, Language, Processing Speed, Working Memory, and Attention. Seven measures were designed to tap constructs within these subdomains. The instruments were validated in English, in a sample of 476 participants ranging in age from 3 to 85 years, with representation from both sexes, 3 racial/ethnic categories, and 3 levels of education. This report describes the development of the Cognition Battery and presents results on test-retest reliability, age effects on performance, and convergent and discriminant construct validity. The NIH-TB Cognition Battery is intended to serve as a brief, convenient set of measures to supplement other outcome measures in epidemiologic and longitudinal research and clinical trials. With a computerized format and national standardization, this battery will provide a "common currency" among researchers for comparisons across a wide range of studies and populations.
认知是 NIH 工具包评估神经和行为功能（NIH-TB）测量的四个领域之一，补充了测试运动功能、感觉和情绪的模块。基于专家小组，确定对健康、学校和工作成功以及日常生活功能独立最重要的认知子领域是执行功能、情景记忆、语言、处理速度、工作记忆和注意力。设计了七种措施来挖掘这些子领域内的结构。这些仪器已在英语中进行了验证，样本包括 476 名年龄在 3 至 85 岁之间的参与者，来自两性、3 个种族/族裔群体和 3 个教育水平。本报告描述了认知电池的开发，并介绍了测试-重测信度、表现的年龄效应以及聚合和区别结构有效性的结果。NIH-TB 认知电池旨在作为一种简短、方便的措施集，补充流行病学和纵向研究以及临床试验中的其他结果措施。采用计算机格式和国家标准，该电池将为研究人员在广泛的研究和人群中进行比较提供“共同货币”。
