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慢性阻塞性肺疾病(COPD)的药物治疗及当前争议

Pharmacological treatment and current controversies in COPD.

作者信息

Cazzola Mario, Rogliani Paola, Stolz Daiana, Matera Maria Gabriella

机构信息

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

Clinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital of Basel, Basel, Switzerland.

出版信息

F1000Res. 2019 Aug 29;8. doi: 10.12688/f1000research.19811.1. eCollection 2019.

Abstract

Bronchodilators, corticosteroids, and antibiotics are still key elements for treating chronic obstructive pulmonary disease in the 2019 Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommendations and this is due in part to our current inability to discover new drugs capable of decisively influencing the course of the disease. However, in recent years, information has been produced that, if used correctly, can allow us to improve the use of the available therapies.

摘要

支气管扩张剂、皮质类固醇和抗生素仍然是2019年慢性阻塞性肺疾病全球倡议(GOLD)推荐的治疗慢性阻塞性肺疾病的关键要素,部分原因在于我们目前无法发现能够决定性地影响该疾病进程的新药。然而,近年来已产生了一些信息,如果正确使用,这些信息能够让我们改进现有疗法的使用。

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本文引用的文献

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5
Adding a LAMA to ICS/LABA Therapy: A Meta-analysis of Triple Combination Therapy in COPD.
Chest. 2019 Apr;155(4):758-770. doi: 10.1016/j.chest.2018.12.016. Epub 2019 Jan 17.
6
Inhaled corticosteroids in COPD: the final verdict is….
Eur Respir J. 2018 Dec 13;52(6). doi: 10.1183/13993003.01940-2018. Print 2018 Dec.
7
Triple therapy single and dual long-acting bronchodilator therapy in COPD: a systematic review and meta-analysis.
Eur Respir J. 2018 Dec 13;52(6). doi: 10.1183/13993003.01586-2018. Print 2018 Dec.
8
9
Anti-inflammatory effects of roflumilast in chronic obstructive pulmonary disease (ROBERT): a 16-week, randomised, placebo-controlled trial.
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10
Inhaled corticosteroid containing combinations and mortality in COPD.
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