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The Ethics of Cerebral Organoid Research: Being Conscious of Consciousness.
Stem Cell Reports. 2019 Sep 10;13(3):440-447. doi: 10.1016/j.stemcr.2019.08.003.
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Potential ethical problems with human cerebral organoids: Consciousness and moral status of future brains in a dish.
Brain Res. 2021 Jan 1;1750:147146. doi: 10.1016/j.brainres.2020.147146. Epub 2020 Oct 15.
3
Mapping the Ethical Issues of Brain Organoid Research and Application.
AJOB Neurosci. 2022 Apr-Jun;13(2):81-94. doi: 10.1080/21507740.2021.1896603. Epub 2021 Mar 26.
4
Media portrayal of ethical and social issues in brain organoid research.
Philos Ethics Humanit Med. 2022 Apr 13;17(1):8. doi: 10.1186/s13010-022-00119-z.
5
Consciousness in a Rotor? Science and Ethics of Potentially Conscious Human Cerebral Organoids.
AJOB Neurosci. 2023 Apr-Jun;14(2):178-196. doi: 10.1080/21507740.2023.2173329. Epub 2023 Feb 15.
6
Knowledge graphs of ethical concerns of cerebral organoids.
Cell Prolif. 2022 Aug;55(8):e13239. doi: 10.1111/cpr.13239. Epub 2022 May 17.
7
Ethical issues related to brain organoid research.
Brain Res. 2020 Apr 1;1732:146653. doi: 10.1016/j.brainres.2020.146653. Epub 2020 Feb 1.
8
Brain organoids, consciousness, ethics and moral status.
Semin Cell Dev Biol. 2023 Jul 30;144:97-102. doi: 10.1016/j.semcdb.2022.03.020. Epub 2022 Mar 23.
10
Cerebral organoids: ethical issues and consciousness assessment.
J Med Ethics. 2018 Sep;44(9):606-610. doi: 10.1136/medethics-2017-104555. Epub 2018 Feb 28.

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2
A tumorigenicity evaluation platform for cell therapies based on brain organoids.
Transl Neurodegener. 2024 Oct 29;13(1):53. doi: 10.1186/s40035-024-00446-5.
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Promoting Alzheimer's disease research and therapy with stem cell technology.
Stem Cell Res Ther. 2024 May 7;15(1):136. doi: 10.1186/s13287-024-03737-w.
4
Assembloid learning: opportunities and challenges for personalized approaches to brain functioning in health and disease.
Front Artif Intell. 2024 Apr 19;7:1385871. doi: 10.3389/frai.2024.1385871. eCollection 2024.
5
Organotypic culture of human brain explants as a preclinical model for AI-driven antiviral studies.
EMBO Mol Med. 2024 Apr;16(4):1004-1026. doi: 10.1038/s44321-024-00039-9. Epub 2024 Mar 12.
6
The Ethics of Human Brain Organoid Transplantation in Animals.
Neuroethics. 2023;16(3):27. doi: 10.1007/s12152-023-09532-3. Epub 2023 Oct 4.
7
The technology, opportunities, and challenges of Synthetic Biological Intelligence.
Biotechnol Adv. 2023 Nov;68:108233. doi: 10.1016/j.biotechadv.2023.108233. Epub 2023 Aug 7.
8
Cerebral Organoid Research Ethics and Pinning the Tail on the Donkey.
Camb Q Healthc Ethics. 2023 May 10;32(4):1-13. doi: 10.1017/S0963180123000221.
9
Human Brain Organoids in Migraine Research: Pathogenesis and Drug Development.
Int J Mol Sci. 2023 Feb 4;24(4):3113. doi: 10.3390/ijms24043113.
10
How collaboration between bioethicists and neuroscientists can advance research.
Nat Neurosci. 2022 Nov;25(11):1399-1401. doi: 10.1038/s41593-022-01187-2.

本文引用的文献

1
Self-Organized Synchronous Calcium Transients in a Cultured Human Neural Network Derived from Cerebral Organoids.
Stem Cell Reports. 2019 Sep 10;13(3):458-473. doi: 10.1016/j.stemcr.2019.05.029. Epub 2019 Jun 27.
2
The moral status of cerebral organoids.
Regen Ther. 2019 Mar 15;10:118-122. doi: 10.1016/j.reth.2019.02.003. eCollection 2019 Jun.
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hESC-Derived Thalamic Organoids Form Reciprocal Projections When Fused with Cortical Organoids.
Cell Stem Cell. 2019 Mar 7;24(3):487-497.e7. doi: 10.1016/j.stem.2018.12.015. Epub 2019 Feb 21.
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Vascularization and Engraftment of Transplanted Human Cerebral Organoids in Mouse Cortex.
eNeuro. 2018 Nov 20;5(6). doi: 10.1523/ENEURO.0219-18.2018. eCollection 2018 Nov-Dec.
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Lab-grown 'mini brains' produce electrical patterns that resemble those of premature babies.
Nature. 2018 Nov;563(7732):453. doi: 10.1038/d41586-018-07402-0.
7
Cerebral organoids and consciousness: how far are we willing to go?
J Med Ethics. 2018 Sep;44(9):613-614. doi: 10.1136/medethics-2018-104976. Epub 2018 Jun 28.
8
Glioblastoma Model Using Human Cerebral Organoids.
Cell Rep. 2018 Apr 24;23(4):1220-1229. doi: 10.1016/j.celrep.2018.03.105.
9
The ethics of experimenting with human brain tissue.
Nature. 2018 Apr;556(7702):429-432. doi: 10.1038/d41586-018-04813-x.
10
An in vivo model of functional and vascularized human brain organoids.
Nat Biotechnol. 2018 Jun;36(5):432-441. doi: 10.1038/nbt.4127. Epub 2018 Apr 16.

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