Department of Pediatrics, Korea University College of Medicine, Seoul, Korea.
Environmental Health Center for Asthma, Korea University Anam Hospital, Seoul, Korea.
Yonsei Med J. 2019 Oct;60(10):952-959. doi: 10.3349/ymj.2019.60.10.952.
The purpose of this study was to investigate the effects of short-term and very short-term exposure to particulate matter (PM) exceeding the daily average environmental standards for Korea (≤100 μg/m³ for PM10 and ≤50 μg/m³ for PM2.5) on on asthma-related hospital visits.
This was a population-based, case-crossover study using National Health Insurance and air pollution data between January 1, 2014 and December 31, 2016. The event day was defined as a day when PM exceeded the daily average environmental standard (short-term exposure) or daily average environmental standard for 2 hours (very short-term exposure). The control day was defined as the same day of the week at 1 week prior to the event day.
Compared with control days, asthma-related hospital visits on the 24-hr event days and 2-hr event days increased by 4.10% and 3.45% for PM₁₀ and 5.66% and 3.74% for PM, respectively. Asthma-related hospital visits increased from the 24-hr event day for PM₁₀ to 4 days after the event day, peaking on the third day after the event day (1.26, 95% confidence interval, 1.22-1.30). Hospitalizations also increased on the third day after the event. While there was a difference in magnitude, PM exposure showed similar trends to PM₁₀ exposure.
We found a significant association between short-term and very short-term PM exposure exceeding the current daily average environmental standards of Korea and asthma-related hospital visits. These results are expected to aid in establishing appropriate environmental standards and relevant policies for PM.
本研究旨在探讨短期和极短期暴露于超过韩国每日环境标准(PM10 为≤100μg/m³,PM2.5 为≤50μg/m³)的颗粒物(PM)对与哮喘相关的医院就诊的影响。
这是一项基于人群的病例交叉研究,使用了国家健康保险和 2014 年 1 月 1 日至 2016 年 12 月 31 日期间的空气污染数据。事件日定义为 PM 超过每日环境平均标准(短期暴露)或每日环境平均标准 2 小时(极短期暴露)的那一天。对照日定义为事件日前一周的同日。
与对照日相比,PM10 的 24 小时事件日和 2 小时事件日的哮喘相关医院就诊分别增加了 4.10%和 3.45%,PM 的相应增加了 5.66%和 3.74%。哮喘相关医院就诊从 PM10 的 24 小时事件日增加到事件日后 4 天,在事件日后第 3 天达到峰值(1.26,95%置信区间 1.22-1.30)。住院治疗也在事件日后第 3 天增加。虽然幅度有所不同,但 PM 暴露与 PM10 暴露显示出相似的趋势。
我们发现,短期和极短期 PM 暴露超过韩国目前的每日环境标准与与哮喘相关的医院就诊之间存在显著关联。这些结果有望为 PM 制定适当的环境标准和相关政策提供帮助。