Emergence of IncX3 Plasmid-Harboring Dominated by ST48 in a Goose Farm in Jiangsu, China.

Twelve carbapenem-resistant strains were obtained from goose farms in Jiangsu, China. These isolates were resistant to multiple antimicrobials, and positive for the . The carbapenem-resistance of all strains mediated by were successfully conjugated to J53. S1-PFGE and WGS results showed was located on IncX3 conjugative plasmids with a size of ca. 46 kb. All -bearing IncX3 plasmids shared the same genetic context almost identical to pNDM_MGR194- and pNDM-QD28- reported in India and China, respectively. The twelve strains belonged to three STs, in which the dominant type of isolated from breeding goose farm carrying was ST48. The emergence of -bearing strains in goose farms and the clonal transmission of within the breeding goose farm highlighted the potential reservoir of carbapenemase genes in waterfowl farming system, which may further contaminate environments and pose a threat to public health. Comprehensive surveillance of carbapenem-resistant bacteria in goose farms warrants further study to evaluate the underlying risks.