Edwards J F, Dodds W J, Slauson D O
Vet Pathol. 1985 Mar;22(2):171-6. doi: 10.1177/030098588502200212.
Pigs infected with an African swine fever field isolate of modified virulence became acutely thrombocytopenic four to five days after the onset of fever and viremia. By eight days after inoculation, all pigs were thrombocytopenic. Immunofluorescence microscopy demonstrated that 2 to 10% of the megakaryocytes were infected. By 13 days after inoculation, platelet counts returned to within normal limits, and there was megakaryocytic hyperplasia despite a continued viremia. Secondary complications delayed the return of normal circulating platelet levels in some pigs. The clinical findings of African swine fever are discussed in light of the gross and histologic lesions.
感染了具有改良毒力的非洲猪瘟野外分离株的猪，在发热和病毒血症发作后的四到五天内会急性血小板减少。接种后八天，所有猪均出现血小板减少。免疫荧光显微镜检查显示，2%至10%的巨核细胞被感染。接种后13天，血小板计数恢复到正常范围内，尽管病毒血症持续存在，但仍有巨核细胞增生。继发性并发症延缓了部分猪正常循环血小板水平的恢复。根据大体和组织学病变对非洲猪瘟的临床发现进行了讨论。
