Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, UPS, Toulouse, France.
Departments of Medicine and Laboratory Medicine, University of California, San Francisco, CA.
Physiology (Bethesda). 2019 Nov 1;34(6):392-401. doi: 10.1152/physiol.00017.2019.
Megakaryocytes are normal cellular components of the blood returning to the heart and entering the lungs, and historical data has pointed to a role of the lungs in platelet production. Recent studies using intravital microscopy have demonstrated that platelet release occurs in the lung from bone marrow megakaryocytes that embolize into the lung circulation.
巨核细胞是血液中的正常细胞成分,它们回到心脏并进入肺部,历史数据表明肺部在血小板生成中起作用。最近使用活体显微镜的研究表明,血小板释放发生在肺部,来自骨髓中的巨核细胞栓塞到肺循环中。