Division of Cardiovascular Diseases, Department of Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
Division of Cardiovascular Diseases, Department of Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
Cardiol Clin. 2019 Nov;37(4):419-427. doi: 10.1016/j.ccl.2019.07.006. Epub 2019 Aug 27.
Heart disease is the most important cause of non-cancer death for patients with cancer. Addressing the cardiotoxic effects of anticancer therapies to prevent increased cardiovascular risk in this population is crucial. Echocardiography plays a big role in monitoring cardiotoxicity induced by cancer treatment. Many emerging modalities, including tissue Doppler imaging measures, speckle tracking imaging, and three-dimensional echocardiography, may provide improved sensitivity and specificity to detect cancer treatment-induced cardiotoxicity. Additional research is critical to define the value of both conventional and novel indices in guiding the clinical management of cancer treatment-induced cardiotoxicity.
心脏病是癌症患者非癌症死亡的最重要原因。解决抗癌治疗的心脏毒性作用，以预防这一人群心血管风险增加至关重要。超声心动图在监测癌症治疗引起的心脏毒性方面发挥着重要作用。许多新兴模式，包括组织多普勒成像测量、斑点追踪成像和三维超声心动图，可能提供更高的敏感性和特异性，以检测癌症治疗引起的心脏毒性。需要进一步的研究来确定传统和新型指标在指导癌症治疗引起的心脏毒性的临床管理中的价值。
