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款冬多糖对含顺铂多药化疗所致肠道上皮损伤作用的纠正

Correction of Damaging Effects of Cisplatin-Containing Polychemotherapy on the Intestinal Epithelium with Tussilago farfara L. Polysaccharides.

作者信息

Safonova E A, Lopatina K A, Razina T G, Zueva E P, Sadrikina L A, Gur'ev A M, Belousov M V

机构信息

E. D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk National Research Medical Center, Tomsk, Russia.

Siberian State Medical University, Ministry of Healthcare of the Russian Federation, Tomsk, Russia.

出版信息

Bull Exp Biol Med. 2019 Sep;167(5):616-620. doi: 10.1007/s10517-019-04582-1. Epub 2019 Oct 12.

DOI:10.1007/s10517-019-04582-1
PMID:31606804
Abstract

A possibility for correction of damaging effects of polychemotherapy on the intestinal epithelium with Tussilago farfara L. polysaccharides was studied on C57Bl/6 mice with Lewis lung carcinoma. The polysaccharides had protective and/or stimulating effects on the intestinal epithelium during polychemotherapy and promoted reparative regeneration in the intestine.

摘要

在患有Lewis肺癌的C57Bl/6小鼠身上，研究了款冬多糖纠正多药化疗对肠上皮损伤作用的可能性。这些多糖在多药化疗期间对肠上皮具有保护和/或刺激作用，并促进肠道的修复性再生。

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