Menadi Salah Eddine, Mura Alessandra, Santucciu Cinzia, Ghalmi Farida, Hafsi Fella, Masala Giovanna
Research Laboratory Management of Local Animal Resources, Higher National Veterinary School "RABIE BOUCHAMA", Street Issad Abbes, Oued Smar, 16270, Algiers, Algeria.
Zoonosis Laboratory, Istituto Zooprofilattico Sperimentale della Sardegna, Via Vienna 2, 07100, Sassari, Italy.
Trop Anim Health Prod. 2020 May;52(3):935-942. doi: 10.1007/s11250-019-02083-x. Epub 2019 Oct 12.
A cross-sectional study was conducted to determine the seroprevalence and the risk factors associated with C. burnetii infection in cattle in the state of Setif in northeastern Algeria from March 2016 to April 2018. A total of 678 cows animals aged at least 24 months and belonging to 90 herds were randomly selected. A serum sample from each cow was tested for antibodies against C. burnetii using an indirect enzyme-linked immunosorbent assay (ELISA). A structured questionnaire focusing on risk factors for C. burnetii infection was administered to farm owners involved in the study. The individual animal prevalence was 11.36% (77/678) (95%CI 8.97-13.75%), the herd prevalence was 45.56% (41/90) (95%CI 35.27-55.84%), and the within-herd prevalence ranged from 9.09 to 57.14% (mean 23.71%; Q1 11.11%, Q2 or median 20%, Q3 30%). Multivariable logistic regression analysis revealed that contact with other herds (odds ratio (OR) 1.95, 95 CI 1.12-3.42) and purchased animals (OR 2.05, 95 CI 1.14-3.68) was identified as risk factors for seropositivity to C. burnetii, while the use of disinfectants (OR 0.32, 95 CI 0.14-0.72) was identified as protective factor. The results from the present study indicate that C. burnetii is circulating into cattle herds in the region of Setif in Northeastern of Algeria. It is recommended to implement good hygienic practices and measures of biosecurity to reduce the spread of infection between cattle herds and possible exposure of humans.
2016年3月至2018年4月，在阿尔及利亚东北部塞提夫省开展了一项横断面研究，以确定牛群中伯氏考克斯氏体感染的血清阳性率及其相关危险因素。共随机选取了来自90个牛群、年龄至少24个月的678头奶牛。使用间接酶联免疫吸附测定法（ELISA）检测每头奶牛血清样本中抗伯氏考克斯氏体的抗体。向参与研究的农场主发放了一份聚焦于伯氏考克斯氏体感染危险因素的结构化问卷。个体动物感染率为11.36%（77/678）（95%置信区间8.97-13.75%），牛群感染率为45.56%（41/90）（95%置信区间35.27-55.84%），牛群内感染率在9.09%至57.14%之间（平均23.71%；第一四分位数11.11%，第二四分位数或中位数20%，第三四分位数30%）。多变量逻辑回归分析显示，与其他牛群接触（比值比（OR）1.95，95%置信区间1.12-3.42）和购入动物（OR 2.05，95%置信区间1.14-3.68）被确定为伯氏考克斯氏体血清阳性的危险因素，而使用消毒剂（OR 0.32，95%置信区间0.14-0.72）被确定为保护因素。本研究结果表明，伯氏考克斯氏体在阿尔及利亚东北部塞提夫地区的牛群中传播。建议实施良好的卫生措施和生物安全措施，以减少牛群间感染的传播以及人类可能的暴露风险。
