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直肠癌患者术后低位前切除综合征评分斯洛文尼亚语版本的验证

Validation of The Slovenian Version of the Low Anterior Resection Syndrome Score for Rectal Cancer Patients after Surgery.

作者信息

Grosek Jan, Košir Jurij Aleš, Novak Jerica, Omejc Mirko, Tomažič Aleš, Norčič Gregor

机构信息

University Medical Centre Ljubljana, Department of Abdominal Surgery, Zaloška cesta 7, 1000 Ljubljana, Slovenia.

Institute of Oncology Ljubljana, Division of Surgery, Zaloška cesta 2, 1000 Ljubljana, Slovenia.

出版信息

Zdr Varst. 2019 Oct 1;58(4):148-154. doi: 10.2478/sjph-2019-0019. eCollection 2019 Dec.

Abstract

PURPOSE

The purpose of this study was to translate the low anterior resection syndrome (LARS) score into Slovenian and to test its validity on Slovenian patients who underwent low anterior rectal resection.

METHODS

The LARS score was translated from English into Slovenian and then back-translated following international recommendations. The Slovenian version of the LARS questionnaire was completed by patients who underwent low anterior rectal resection between 1 January 2006 and 31 December 2010 at the University Medical Centre Ljubljana. An anchor question assessing the impact of bowel function on lifestyle was included. To assess test-retest reliability, some of the patients answered the LARS score questionnaire twice.

RESULTS

A total of 100 patients (66.7%) of the 150 patients who were contacted for participation, were included in the final analysis. A total of 58 patients reported major LARS score. The LARS score was able to discriminate between patients who received radiotherapy and those who did not (p<0.001), and between total and partial mesorectal excision (p<0.001). Age was not associated with a greater LARS score (p=0.975). There was a perfect fit between the QoL category question and the LARS score in 66.0% of cases and a moderate fit was found in 24.0% of the cases, showing good convergent validity. Test-retest reliability of 51 patients showed a high intraclass correlation coefficient of 0.86.

CONCLUSIONS

The Slovenian translation of the LARS score is a valid tool for measuring LARS.

摘要

目的

本研究旨在将低位前切除综合征(LARS)评分翻译成斯洛文尼亚语,并在接受低位直肠前切除术的斯洛文尼亚患者中测试其有效性。

方法

按照国际建议将LARS评分从英语翻译成斯洛文尼亚语,然后再进行回译。2006年1月1日至2010年12月31日在卢布尔雅那大学医学中心接受低位直肠前切除术的患者完成了斯洛文尼亚语版的LARS问卷。其中包含一个评估肠道功能对生活方式影响的关键问题。为评估重测信度,部分患者两次回答LARS评分问卷。

结果

在联系参与研究的150名患者中,共有100名患者(66.7%)纳入最终分析。共有58名患者报告LARS评分较高。LARS评分能够区分接受放疗和未接受放疗的患者(p<0.001),以及全直肠系膜切除和部分直肠系膜切除的患者(p<0.001)。年龄与较高的LARS评分无关(p=0.975)。66.0%的病例中生活质量类别问题与LARS评分完全匹配,24.0%的病例中存在中度匹配,显示出良好的收敛效度。51名患者的重测信度显示组内相关系数高达0.86。

结论

LARS评分的斯洛文尼亚语翻译是测量LARS的有效工具。

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