Kim Chang Woo, Jeong Woon Kyung, Son Gyung Mo, Kim Ik Yong, Park Ji Won, Jeong Seung-Yong, Park Kyu Joo, Lee Suk-Hwan
Department of Surgery, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Korea.
Department of Surgery, Keimyung University Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea.
Ann Coloproctol. 2020 Apr;36(2):83-87. doi: 10.3393/ac.2019.08.01. Epub 2020 Feb 11.
Patients who undergo radical surgery for rectal cancer often experience low anterior resection syndrome (LARS). Symptoms of this syndrome include frequent bowel movements, gas incontinence, fecal incontinence, fragmentation, and urgency. The aim of this study was to investigate the convergent validity, discriminative validity, and reliability of the Korean version of the LARS score questionnaire.
The English LARS score questionnaire was translated into Korean using the forward-and-back translation method. A total of 146 patients who underwent radical surgery for rectal cancer answered the Korean version of the LARS score questionnaire including an anchor question assessing the impact of bowel function. Participants answered the questionnaire once more after 2 weeks.
The Korean LARS score questionnaire showed high convergent validity in terms of high correlation between the LARS score and quality of life (perfect fit 55.5% vs. moderate fit 37.6% vs. no fit 6.8%, respectively; P < 0.001). The LARS score also showed good discriminative validity between groups of patients differing by sex (29 for males vs. 25 for females; P = 0.014), tumor level (29 for ≤8 cm vs. 24 for >8 cm; P = 0.021), and radiotherapy (32 for yes vs. 24 for no; P = 0.001). The LARS score also demonstrated high reliability at test-retest with no difference between scores at the first and second tests (intraclass correlation coefficient: Q1 = 0.932; Q2 = 0.909, Q3 = 0.944, Q4 = 0.931, and Q5 = 0.942; P < 0.001, respectively).
The Korean version of the LARS score questionnaire has proven to be a valid and reliable tool for measuring LARS in Korean patients with rectal cancer.
接受直肠癌根治手术的患者常出现低位前切除综合征（LARS）。该综合征的症状包括排便频繁、气体失禁、粪便失禁、粪便碎片化和便急。本研究的目的是调查韩语版LARS评分问卷的收敛效度、区分效度和信度。
采用正向和反向翻译法将英文LARS评分问卷翻译成韩语。共有146例接受直肠癌根治手术的患者回答了韩语版LARS评分问卷，其中包括一个评估肠道功能影响的锚定问题。参与者在2周后再次回答该问卷。
韩语版LARS评分问卷在LARS评分与生活质量之间的高相关性方面显示出高收敛效度（完全符合分别为55.5%、中度符合为37.6%、不符合为6.8%；P<0.001）。LARS评分在不同性别（男性为29分，女性为25分；P = 0.014）、肿瘤水平（≤8 cm为29分，>8 cm为24分；P = 0.021）和放疗（是为32分，否为24分；P = 0.001）的患者组之间也显示出良好的区分效度。LARS评分在重测时也显示出高信度，第一次和第二次测试的分数之间没有差异（组内相关系数：Q1 = 0.932；Q2 = 0.909，Q3 = 0.944，Q4 = 0.931，Q5 = 0.942；P<0.001）。
韩语版LARS评分问卷已被证明是测量韩国直肠癌患者LARS的有效且可靠的工具。
