Malamed S F, Nikchevich D, Block J
Anesth Prog. 1988 Jul-Aug;35(4):160-2.
Anterograde amnesia is often considered to be a beneficial effect of intravenous conscious sedation. The recently introduced benzodiazepine, midazolam, has associated with its administration a significant anterograde amnesic period. In the case presented here, a healthy young female presented for third molar extraction under midazolam conscious sedation and local anesthesia. After uncomplicated removal of the teeth and clinically adequate recovery from sedation, it was noted that the patient had swallowed the postsurgical gauze packs. Efforts at recovery of the gauze packs were futile. Follow-up discussion with the patient revealed a complete lack of recall of all events occurring for up to an hour or more after the administration of intravenous midazolam. The need for written and oral postoperative instructions to both the patient and his/her escort is emphasized.
顺行性遗忘常被认为是静脉注射清醒镇静的一种有益效果。最近引入的苯二氮䓬类药物咪达唑仑，在给药后会出现显著的顺行性遗忘期。在此病例中，一名健康的年轻女性在咪达唑仑清醒镇静和局部麻醉下接受第三磨牙拔除术。在牙齿顺利拔除且镇静后临床恢复良好的情况下，发现患者吞下了术后的纱布块。尝试找回纱布块的努力徒劳无功。与患者的后续讨论显示，患者对静脉注射咪达唑仑后长达一小时或更长时间内发生的所有事件完全没有记忆。强调了对患者及其陪同人员进行书面和口头术后指导的必要性。
