Department of Food and Nutrition, Chung-Ang University, Gyeonggi-do, 17546 Korea.
Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, 03080 Korea.
Appl Physiol Nutr Metab. 2019 Dec;44(12):1371-1378. doi: 10.1139/apnm-2018-0880. Epub 2019 Oct 30.
The aim of this study was to evaluate the association between the frequency and quantity of coffee consumption and metabolic syndrome (MetS) in the Health Examinees study. A total of 130 420 participants (43 682 men and 86 738 women) were included in our study. Coffee consumption was categorized into 5 categories (0, <1, 1, 2-3, and ≥4 cups/day). We calculated odds ratios (ORs) and 95% confidence intervalS (CIs) using multivariate logistic regression. In this study population, the prevalence of MetS was 12 701 (29.1%) in men and 21 338 (24.6%) in women. High coffee consumption (≥4 cups/day) was associated with a lower prevalence of MetS compared with non-coffee consumers (OR = 0.79, 95% CI = 0.70-0.90, for trend <0.0001 in men; OR = 0.70, 95% CI = 0.62-0.78, for trend <0.0001 in women). The multivariable-adjusted ORs for high fasting glucose decreased with increasing levels of coffee consumption in men (OR = 0.60, 95% CI = 0.54-0.67, for trend <0.0001) and women (OR = 0.70, 95% CI = 0.63-0.79, for trend <0.0001). For women, the multivariable-adjusted ORs for hypertriglyceridemia (OR = 0.84, 95% CI = 0.75-0.93, for trend = 0.0007) decreased with increasing levels of coffee consumption. We found that coffee consumption was inversely associated with the prevalence of metabolic syndrome among Korean men and women. Our study warrants further prospective cohort studies.
本研究旨在评估咖啡摄入频率和摄入量与代谢综合征（MetS）之间的关联。共有 130420 名参与者（43682 名男性和 86738 名女性）纳入本研究。咖啡摄入量分为 5 类（0、<1、1、2-3 和≥4 杯/天）。我们使用多变量 logistic 回归计算比值比（OR）和 95%置信区间（CI）。在本研究人群中，男性代谢综合征的患病率为 12701 例（29.1%），女性为 21338 例（24.6%）。与非咖啡消费者相比，大量饮用咖啡（≥4 杯/天）与代谢综合征的患病率较低相关（男性：OR=0.79，95%CI=0.70-0.90，趋势<0.0001；女性：OR=0.70，95%CI=0.62-0.78，趋势<0.0001）。男性高血糖的多变量调整 OR 随着咖啡摄入量的增加而降低（OR=0.60，95%CI=0.54-0.67，趋势<0.0001），女性高血糖的多变量调整 OR 随着咖啡摄入量的增加而降低（OR=0.70，95%CI=0.63-0.79，趋势<0.0001）。对于女性，随着咖啡摄入量的增加，高甘油三酯血症的多变量调整 OR（OR=0.84，95%CI=0.75-0.93，趋势=0.0007）降低。我们发现，咖啡摄入量与韩国男性和女性代谢综合征的患病率呈负相关。我们的研究需要进一步的前瞻性队列研究。
