两性霉素B与卡泊芬净联合治疗毛霉病

Combination of amphotericin B and caspofungin in the treatment of mucormycosis.

作者信息

Gargouri Marwa, Marrakchi Chakib, Feki Wiem, Charfi Slim, Maaloul Imed, Lahiani Dorra, Elleuch Emna, Koubaa Makram, Mnif Zineb, Ayadi Ali, Boudawara Tahiya, Ben Jemaa Mounir

机构信息

Department of Infectious Diseases, Hedi Chaker University Hospital, Sfax, Tunisia.

Department of Radiology, Hedi Chaker University Hospital, Sfax, Tunisia.

出版信息

Med Mycol Case Rep. 2019 Sep 21;26:32-37. doi: 10.1016/j.mmcr.2019.09.006. eCollection 2019 Dec.

We report a case of invasive mucormycosis in 52 year-old woman. CT-scan and magnetic resonance imaging found a partial right sinus thrombosis associated with homolateral ethmoidal and maxillary sinusitis with submucosal inflammation. Histopathological examination of excised tissue was positive for mucormycosis. Our patient was treated by surgical debridement and a combination of amphotericin B and caspofungin, with a good outcome.