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2017年伊朗北部戈勒斯坦省戈尔甘参考实验室送检人群中包虫病血清阳性率

Seroprevalence of Hydatidosis in People Referring to Reference Laboratory of Gorgan, Golestan Province, Northern Iran 2017.

作者信息

Fathi Saman, Ghasemikhah Reza, Mohammadi Rasool, Tohidi Farideh, Sharbatkhori Mitra

机构信息

Student Research Committee, Arak University of Medical Sciences, Arak, Iran.

Infectious Diseases Research Center (IDRC), Arak University of Medical Sciences, Arak, Iran.

出版信息

Iran J Parasitol. 2019 Jul-Sep;14(3):436-443.

Abstract

BACKGROUND

Hydatidosis is a neglected global zoonotic disease, caused by larval stage of the cestode in human and animal. Because of high economic and medical importance of the disease, this study was performed to find the seroprevalence of human hydatidosis in Gorgan City, Golestan Province, northern Iran.

METHODS

In this cross-sectional study, blood samples were collected from people referring to Reference laboratory of Golestan University of Medical sciences in 2017. A relevant questionnaire was completed for demographic data for each person. IgG antibody was investigated by ELISA using native antigen B. The data were analyzed using SPSS software applying logistic regression.

RESULTS

Overall, 612 blood samples were collected. Cut-off was considered 0.29. Sixteen cases (2.6%) were seropositive for hydatidosis. The seroprevalence of hydatidosis was 2.3% and 4.7% among males and females, respectively. There was no statistically significant correlation between the hydatidosis and investigated variables such as sex, age, tribes, residence, education, etc.

CONCLUSION

The prevalence of human hydatidosis shows approximately the same range as other regions of Iran. Although due to the neighboring the Mazandaran Province reported as the highest seroprevalence of hydatidosis, we expected more rate of seropositivity.

摘要

背景

包虫病是一种被忽视的全球性人畜共患病,由绦虫幼虫阶段感染人和动物引起。鉴于该疾病在经济和医学上的高度重要性,本研究旨在确定伊朗北部戈勒斯坦省戈尔甘市人类包虫病的血清流行率。

方法

在这项横断面研究中,于2017年从前往戈勒斯坦医科大学参考实验室就诊的人群中采集血样。为每个人填写一份相关问卷以获取人口统计学数据。使用天然抗原B通过酶联免疫吸附测定法(ELISA)检测IgG抗体。使用SPSS软件应用逻辑回归分析数据。

结果

总共采集了612份血样。临界值设定为0.29。16例(2.6%)包虫病血清学检测呈阳性。包虫病血清流行率在男性和女性中分别为2.3%和4.7%。包虫病与所调查变量如性别、年龄、部落、居住地、教育程度等之间无统计学显著相关性。

结论

人类包虫病的流行率与伊朗其他地区大致相同。尽管由于与马赞德兰省相邻,该省报告的包虫病血清流行率最高,但我们预期的血清阳性率更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60ea/6815868/b3d625f99891/IJPA-14-436-g001.jpg

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