Chongqing Key Laboratory of Green Synthesis and Applications, College of Chemistry , Chongqing Normal University , Chongqing 401331 , China.
ACS Appl Mater Interfaces. 2019 Nov 27;11(47):44466-44473. doi: 10.1021/acsami.9b17488. Epub 2019 Nov 18.
A metal-organic framework (MOF) [Cu(PDA)(DMF)] was synthesized under mild mixed solvothermal conditions. It is constructed by 1,10-phenanthroline-2,9-dicarboxylic acid (HPDA) and Cu ions. The complex exhibits high peroxidase-like activity and can catalytically oxidize the colorless substrate 3,3',5,5'-tetramethylbenzidine to a blue product in the presence of HO. However, the peroxidase-like activity of [Cu(PDA)(DMF)] can be potently inhibited in the presence of dopamine. Based on this phenomenon, the colorimetric detection of dopamine was demonstrated with good selectivity and high sensitivity. [Cu(PDA)(DMF)] showed good stability and robust catalytic activity, which has been employed in the detection of dopamine in human urine and pharmaceutical samples.
一种金属-有机框架（MOF）[Cu(PDA)(DMF)]在温和的混合溶剂热条件下合成。它由 1,10-菲啰啉-2,9-二羧酸（HPDA）和 Cu 离子构建。该配合物具有高过氧化物酶样活性，在 HO 的存在下可以催化无色底物 3,3',5,5'-四甲基联苯胺氧化为蓝色产物。然而，[Cu(PDA)(DMF)]的过氧化物酶样活性在多巴胺的存在下可以被强烈抑制。基于这一现象，实现了多巴胺的比色检测，具有良好的选择性和高灵敏度。[Cu(PDA)(DMF)]表现出良好的稳定性和稳健的催化活性，已用于人尿和药物样品中多巴胺的检测。
