Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
Faculty of Medicine, University of Zurich, Zurich, Switzerland.
J Dermatolog Treat. 2021 Feb;32(1):104-109. doi: 10.1080/09546634.2019.1690621. Epub 2019 Nov 20.
Colchicine is an ancient, but rarely used drug. Little data exist on its efficacy and safety in patients suffering from skin diseases. The objective of our study was to determine whether colchicine showed favorable efficacy and safety in our patients during the last 20 years. The hospital database was searched for patients treated with colchicine in the last 20 years (January 1, 1998 to December 31, 2017). Overall, total of 41 patients were included in our study. In 63.4% of all patients, either a complete response or an improvement of disease was observed. Adverse events occurred rarely. Colchicine is an effective and safe treatment.
秋水仙碱是一种古老但很少使用的药物。关于其在皮肤病患者中的疗效和安全性的数据很少。我们的研究目的是确定在过去 20 年中，秋水仙碱在我们的患者中是否表现出良好的疗效和安全性。我们对医院数据库进行了检索，以寻找在过去 20 年内（1998 年 1 月 1 日至 2017 年 12 月 31 日）接受秋水仙碱治疗的患者。总共纳入了 41 名患者。在所有患者中，63.4%的患者观察到完全缓解或疾病改善。不良反应很少发生。秋水仙碱是一种有效且安全的治疗方法。
