Hegde S A, Hara H, Kobayashi S
Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan.
Histochemistry. 1988;89(5):415-20. doi: 10.1007/BF00492596.
The perivascular innervation of extraparenchymal arteries of spinal cord and the radicular arteries was examined using histochemical and immunohistochemical technics in monkey. The radicular and the extraparenchymal arteries of spinal cord were found to be invested with adrenergic, neuropeptide Y, vasoactive intestinal peptide, substance P and calcitonin gene-related peptide containing nerve fibres. The pattern of arrangement of fibres differed among the various fibre types. SP- and CGRP-containing fibres were less in density as compared to other nerve plexus. There was no difference in density of an individual type of nerve fibre in arteries of different cord segments or between the radicular arteries from different levels. The study reveals the existence of a comprehensive perivascular adrenergic and peptidergic innervation of spinal cord arterial system, with a possible role in neurogenic regulation of spinal cord circulation.
利用组织化学和免疫组织化学技术，在猴子身上对脊髓实质外动脉和根动脉的血管周围神经支配进行了检查。发现脊髓的根动脉和实质外动脉都有含肾上腺素能、神经肽Y、血管活性肠肽、P物质和降钙素基因相关肽的神经纤维。不同类型纤维的排列模式有所不同。与其他神经丛相比，含P物质和降钙素基因相关肽的纤维密度较低。不同脊髓节段动脉中或不同水平根动脉中，单一类型神经纤维的密度没有差异。该研究揭示了脊髓动脉系统存在全面的血管周围肾上腺素能和肽能神经支配，可能在脊髓循环的神经源性调节中发挥作用。
