Xu Delin, Pan Yinchi, Chen Jishuang
Department of Cell Biology, Zunyi Medical University, Zunyi, China.
Key Laboratory of Basic Pharmacology and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China.
Front Pharmacol. 2019 Nov 1;10:1168. doi: 10.3389/fphar.2019.01168. eCollection 2019.
is a plant from the Orchidaceae family that has been employed as a traditional Chinese medicine (TCM) for thousands of years in China. Here, we briefly review the published studies of the last 30 years that were related to chemical constituents, pharmacologic activities, and clinical applications of . Approximately 158 compounds have been extracted from tubers with clarified molecular structures that were classified as glucosides, bibenzyls, phenanthrenes, quinones, biphenanthrenes, dihydrophenanthrenes, anthocyanins, steroids, triterpenoids, and phenolic acids. These chemicals support the pharmacological properties of hemostasis and wound healing, and also exhibit anti-oxidation, anti-cancer, anti-viral, and anti-bacterial activities. Additionally, various clinical trials conducted on have demonstrated its marked activities as an embolizing and mucosa-protective agent, and its application for use in novel biomaterials, quality control, and toxicology. It also has been widely used as a constituent of many preparations in TCM formulations, but because there are insufficient studies on its clinical properties, its efficacy and safety cannot be established from a scientific point of view. We hope that this review will provide reference for further research and development of this unique plant.
是一种来自兰科的植物，在中国作为传统中药使用了数千年。在此，我们简要回顾过去30年中与该植物的化学成分、药理活性和临床应用相关的已发表研究。从该植物块茎中提取了约158种具有明确分子结构的化合物，这些化合物被分类为糖苷、联苄、菲、醌、联菲、二氢菲、花青素、甾体、三萜和酚酸。这些化学成分具有止血和伤口愈合的药理特性，还表现出抗氧化、抗癌、抗病毒和抗菌活性。此外，对该植物进行的各种临床试验证明了其作为栓塞剂和粘膜保护剂的显著活性，以及其在新型生物材料、质量控制和毒理学方面的应用。它也被广泛用作许多中药制剂的成分，但由于对其临床特性的研究不足，从科学角度无法确定其疗效和安全性。我们希望这篇综述能为这种独特植物的进一步研究和开发提供参考。
