Parik Paresh C, Patel Varsha Jitendra
Dr. Jivraj Mehta Smarak Health Foundation, Bakeri Medical Research Centre, Dr. Jivraj Mehta Marg, Paldi, Gujarat, India.
Department of Pharmacology, Dr. M.K. Shah Medical College and Research Centre, Chandkheda, Ahmedabad, Gujarat, India.
Indian J Endocrinol Metab. 2019 Jul-Aug;23(4):407-411. doi: 10.4103/ijem.IJEM_29_19.
To assess the health-related quality of life of Type 2 Diabetes mellitus patients attending outpatient departments of a tertiary hospital using EQ-5D-5L.
The study was conducted at a tertiary care hospital in India. The quality of life of patients with type 2 Diabetes mellitus, age 18 years and older, attending outpatient departments of Medicine and Endocrinology was assessed with the help of EQ-5D-5L, a measure of self-reported health related quality of life. Data was analyzed to obtain EQ-5D-5L scores for the five dimensions and EQ VAS score. Correlation of EQ VAS score with different variables was analyzed.
Out of total 358 participants, 208 had comorbidities, hypertension being the most common. Mean age was 60.71 ± 11.41 years and 216 (58.9%) were female participants. Out of five dimensions, Mobility, Self-care, Usual activities, and Pain/discomfort were most affected in age group 71 years and above while anxiety/depression affected age group 18-30 years the most. Mean EQ VAS score was 78.83 ± 15.02. Female participants had significantly higher EQ VAS score ( = 0.00) than male participants. EQ VAS score showed significant negative correlation with uncontrolled state of diabetes ( = 0.000). There was significant difference in EQ VAS score between patients with and without comorbidities. ( =0.004) Cronbach alpha for EQ-5D-5L was 0.76.
The results suggest that EQ-5D-5L is a reliable measure for assessing health related quality of life of patients with Type 2 Diabetes mellitus. Type 2 Diabetes adversely affects the quality of life of patients. Uncontrolled disease and comorbidities can further compromise the quality of life.
使用EQ-5D-5L评估一家三级医院门诊2型糖尿病患者的健康相关生活质量。
该研究在印度的一家三级护理医院进行。借助EQ-5D-5L(一种自我报告的健康相关生活质量测量工具)对年龄在18岁及以上、前往内科和内分泌科门诊的2型糖尿病患者的生活质量进行评估。对数据进行分析以获得五个维度的EQ-5D-5L分数和EQ VAS分数。分析EQ VAS分数与不同变量之间的相关性。
在总共358名参与者中,208人患有合并症,高血压最为常见。平均年龄为60.71±11.41岁,女性参与者有216人(58.9%)。在五个维度中,71岁及以上年龄组的行动能力、自我护理、日常活动和疼痛/不适受影响最大,而焦虑/抑郁对18 - 30岁年龄组影响最大。平均EQ VAS分数为78.83±15.02。女性参与者的EQ VAS分数显著高于男性参与者(P = 0.00)。EQ VAS分数与糖尿病未控制状态呈显著负相关(P = 0.000)。有合并症和无合并症患者的EQ VAS分数存在显著差异(P = 0.004)。EQ-5D-5L的Cronbach阿尔法系数为0.76。
结果表明,EQ-5D-5L是评估2型糖尿病患者健康相关生活质量的可靠指标。2型糖尿病对患者的生活质量有不利影响。疾病未控制和合并症会进一步损害生活质量。