Department of Para-Clinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.
Independent Researcher, Berlin, Germany.
Front Public Health. 2023 Jun 30;11:1163360. doi: 10.3389/fpubh.2023.1163360. eCollection 2023.
The aim of our study was to validate a German translation of the post-acute (long) COVID-19 quality of life (PAC-19QoL) instrument among German patients with long COVID-19 syndrome.
The PAC-19QoL instrument was translated into the German language and administrated to patients with long COVID-19 syndrome. Cronbach's alpha coefficient was used to analyze the internal consistency of the instrument. Construction validity was evaluated by using Pearson's correlation coefficient and Spearman's rank correlation. Scores of patients and controls were compared using the Mann-Whitney -test.
A total of 45 asymptomatic and 41 symptomatic participants were included. In total, 41 patients with long COVID-19 syndrome completed the PAC-19QoL and EQ-5D-5L questionnaires. PAC-19QoL domain scores were significantly different between symptomatic and asymptomatic participants. All items achieved a Cronbach's alpha >0.7. There was a significant correlation between all domains on the test ( < 0.001), with the highest correlation between total ( = 0.994) and domain 1 ( = 0.991). Spearman's rank correlation analysis confirmed that the instrument items correlated with the objective PAC-19QoL examination findings.
The German version of the instrument is valid and reliable and can be a suitable tool for research and daily clinical practice among patients with long COVID-19 syndrome.
本研究的目的是验证一种针对德国长新冠患者的 PAC-19QoL （后急性（长）新冠生活质量）工具的德语翻译版本。
我们将 PAC-19QoL 工具翻译成德语，并对长新冠综合征患者进行了管理。我们使用 Cronbach's alpha 系数来分析工具的内部一致性。采用 Pearson 相关系数和 Spearman 等级相关来评估结构有效性。使用 Mann-Whitney U 检验比较患者和对照组的得分。
共纳入 45 名无症状和 41 名有症状的参与者。共有 41 名长新冠患者完成了 PAC-19QoL 和 EQ-5D-5L 问卷。PAC-19QoL 领域得分在有症状和无症状参与者之间存在显著差异。所有项目的 Cronbach's alpha 均>0.7。所有测试项目之间均存在显著相关性（<0.001），其中总分（=0.994）和第 1 领域（=0.991）之间的相关性最高。Spearman 等级相关分析证实，工具项目与客观的 PAC-19QoL 检查结果相关。
该工具的德语版本具有有效性和可靠性，可作为长新冠综合征患者研究和日常临床实践的合适工具。
