UNSW Medicine, University of NSW, Randwick, NSW 2031, Australia.
School of Women's & Children's Health, UNSW Medicine, University of NSW, Randwick, NSW 2031, Australia.
Nutrients. 2019 Nov 19;11(11):2835. doi: 10.3390/nu11112835.
Emerging research demonstrates polyphenol-rich diets like the Mediterranean diet may play a role in improving the outcomes of adult cancer therapy. To date, there are no trials assessing the intake or efficacy of polyphenol-rich diets in childhood cancer patients. In this study we collected dietary data on 59 childhood cancer patients on treatment using a three-pass 24-h dietary recall (24-HDR), which is based on a validated and structured three-part methodology. Polyphenol consumption was calculated by matching the food consumption data with polyphenol content extracted from the most updated Phenol-Explorer database. The mean total polyphenol intake was 173.31 ± 141.02 mg/day. The major food sources of polyphenols were fruits, beverages, and cereals. There were no significant associations with time since diagnosis, body mass index (BMI) z-score, types of cancer, treatment intensity, food-related symptoms, relapse, and total daily polyphenol intake. Further investigation with larger studies will facilitate the steps in assessing the value of polyphenol-rich dietary patterns in future nutritional interventions for childhood cancer patients.
新兴研究表明，富含多酚的饮食，如地中海饮食，可能在改善成人癌症治疗效果方面发挥作用。迄今为止，尚无研究评估富含多酚的饮食在儿童癌症患者中的摄入量或疗效。在这项研究中，我们使用经过验证和结构化的三部分方法的三阶段 24 小时膳食回忆法（24-HDR）收集了 59 名正在接受治疗的儿童癌症患者的饮食数据。通过将食物消费数据与从最新 Phenol-Explorer 数据库中提取的多酚含量进行匹配来计算多酚的消费。多酚的总摄入量平均值为 173.31 ± 141.02mg/天。多酚的主要食物来源是水果、饮料和谷物。多酚摄入量与诊断后时间、体重指数（BMI）z 评分、癌症类型、治疗强度、与食物相关的症状、复发以及每日总多酚摄入量均无显著关联。进一步的大型研究将有助于评估富含多酚的饮食模式在未来儿童癌症患者营养干预中的价值。
