2018年埃塞俄比亚阿姆哈拉州奥罗米亚区阿尔图马·富尔西县麻疹疫情调查：一项病例对照研究
Measles outbreak investigation in Artuma Fursi Woreda, Oromia Zone, Amhara Region, Ethiopia, 2018: a case control study.
作者信息
Tariku Mengistie Kassahun, Misikir Sewnet Wongiel
机构信息
Aneded Woreda Health Office, East Gojjam, Amhara Region, Ethiopia.
Felege Hiote Specialized Referral Hospital, Bahir Dar, Ethiopia.
出版信息
BMC Res Notes. 2019 Nov 21;12(1):765. doi: 10.1186/s13104-019-4806-y.
OBJECTIVE
To confirm the existence of Outbreak, describe cases in person, place and time, and identify determinants of the outbreak. Unmatched case control study in the ratio of 1:4 (38 cases and 152 controls) was conducted in Artuma Fursi Woreda from July 13 to August 1/2018. Data were collected with standard questionnaires. Collected data were entered into Epi Info version 7 and exported to Statistical package for social science (SPSS) version 23 for analysis.
RESULTS
A total of 38 cases and 1 death with attack rate and case fatality rate 11.8/100,000 and 2.6%, respectively. All study participants had not vaccination history. Females and age group 5-14 were more affected. Being 5-14 years old versus (vs) ≥ 15 years [adjusted odd ratio (AOR) = 3.53; 95% CI 1.52-8.45)], contact with cases vs no contact with cases [AOR = 2.78; 95% CI 1.23-8.67] and travel history 7-18 days prior onset of illness vs no travel history [AOR = 2.53; 95% CI 1.31-7.24] were significantly associated with contracting measles. Routine and supplement immunization should be strengthened to reduce future occurrence of outbreak.
目的
确认疫情的存在，从人员、地点和时间方面描述病例情况，并确定疫情的决定因素。2018年7月13日至8月1日在阿尔图马富尔西县开展了一项病例对照研究，病例与对照比例为1:4（38例病例和152名对照）。通过标准问卷收集数据。收集到的数据录入Epi Info 7版本，并导出到社会科学统计软件包（SPSS）23版本进行分析。
结果
共38例病例，1例死亡，罹患率和病死率分别为11.8/100,000和2.6%。所有研究参与者均无疫苗接种史。女性和5 - 14岁年龄组受影响更大。5 - 14岁与≥15岁相比[调整优势比（AOR）= 3.53；95%置信区间1.52 - 8.45]，接触病例与未接触病例相比[AOR = 2.78；95%置信区间1.23 - 8.67]，发病前7 - 18天有旅行史与无旅行史相比[AOR = 2.53；95%置信区间1.31 - 7.24]，均与感染麻疹显著相关。应加强常规和补充免疫，以减少未来疫情的发生。
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