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Effects of Statins on Memory, Cognition, and Brain Volume in the Elderly.他汀类药物对老年人记忆力、认知能力和大脑体积的影响。
J Am Coll Cardiol. 2019 Nov 26;74(21):2554-2568. doi: 10.1016/j.jacc.2019.09.041.
2
Patient-Reported Reasons for Declining or Discontinuing Statin Therapy: Insights From the PALM Registry.患者拒绝或停止他汀类药物治疗的原因报告：来自 PALM 注册研究的见解。
J Am Heart Assoc. 2019 Apr 2;8(7):e011765. doi: 10.1161/JAHA.118.011765.
3
Causal associations of blood lipids with risk of ischemic stroke and intracerebral hemorrhage in Chinese adults.血脂与中国成年人缺血性卒中和脑出血风险的因果关联。
Nat Med. 2019 Apr;25(4):569-574. doi: 10.1038/s41591-019-0366-x. Epub 2019 Mar 11.
4
Unraveling the Paradox of Statins with Human Neurons: New Leads in Alzheimer's Disease.揭开他汀类药物治疗阿尔茨海默病悖论的面纱：人类神经元研究的新线索。
Cell Stem Cell. 2019 Mar 7;24(3):347-349. doi: 10.1016/j.stem.2019.02.003.
5
Does taking statins affect the pathological burden in autopsy-confirmed Alzheimer's dementia?服用他汀类药物是否会影响尸检证实的阿尔茨海默病痴呆的病理负担？
Alzheimers Res Ther. 2018 Oct 2;10(1):104. doi: 10.1186/s13195-018-0430-7.
6
Statins use and risk of dementia: A dose-response meta analysis.他汀类药物的使用与痴呆风险：一项剂量反应荟萃分析。
Medicine (Baltimore). 2018 Jul;97(30):e11304. doi: 10.1097/MD.0000000000011304.
7
Use of statins and the risk of dementia and mild cognitive impairment: A systematic review and meta-analysis.使用他汀类药物与痴呆和轻度认知障碍风险的关系：系统评价和荟萃分析。
Sci Rep. 2018 Apr 11;8(1):5804. doi: 10.1038/s41598-018-24248-8.
8
Comparative effect of statins on the risk of incident Alzheimer disease.他汀类药物对阿尔茨海默病发病风险的影响比较。
Neurology. 2018 Jan 16;90(3):e179-e187. doi: 10.1212/WNL.0000000000004818. Epub 2017 Dec 15.
9
Adverse events associated with unblinded, but not with blinded, statin therapy in the Anglo-Scandinavian Cardiac Outcomes Trial-Lipid-Lowering Arm (ASCOT-LLA): a randomised double-blind placebo-controlled trial and its non-randomised non-blind extension phase.在 Anglo-Scandinavian Cardiac Outcomes Trial-Lipid-Lowering Arm（ASCOT-LLA）中，与未设盲、但与设盲他汀类药物治疗相关的不良事件：一项随机、双盲、安慰剂对照试验及其非随机、非盲扩展阶段。
Lancet. 2017 Jun 24;389(10088):2473-2481. doi: 10.1016/S0140-6736(17)31075-9. Epub 2017 May 2.
10
Interpretation of the evidence for the efficacy and safety of statin therapy.他汀类药物治疗疗效和安全性证据解读。
Lancet. 2016 Nov 19;388(10059):2532-2561. doi: 10.1016/S0140-6736(16)31357-5. Epub 2016 Sep 8.

Statins and Cognitive Impairment: Not a Culprit, Protective in Some?

作者信息

Iadecola Costantino, Parikh Neal S

机构信息

Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York; Department of Neurology, Weill Cornell Medicine, New York, New York.

Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, New York, New York; Department of Neurology, Weill Cornell Medicine, New York, New York. Electronic address: https://twitter.com/NealSParikhMD.

出版信息

J Am Coll Cardiol. 2019 Nov 26;74(21):2569-2571. doi: 10.1016/j.jacc.2019.09.040.

DOI:10.1016/j.jacc.2019.09.040
PMID:31753201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7036086/
Abstract
摘要