Mishra Trinath Kumar, Mishra Sura Kishor, Singh Subhasish
M.K.C.G. Medical College & Hospital, Berhampur, India.
M.K.C.G. Medical College & Hospital, Berhampur, India.
Indian Heart J. 2019 Jul-Aug;71(4):338-343. doi: 10.1016/j.ihj.2019.09.006. Epub 2019 Sep 9.
To study the profile and characteristics of cardiovascular abnormalities among patients living with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) at a tertiary care hospital in India. The association of cardiovascular abnormalities with the CD4 count and disease stages, according to the World Health Organization (WHO) classification, was also analyzed.
A total of 200 patients with HIV/AIDS were compared with 50 healthy controls. All patients underwent blood investigations, chest X-ray, electrocardiography, and echocardiography.
The mean age of the patients was 38.66 ± 9.22 years, with a male-to-female ratio of 3.25:1. Echocardiographic abnormalities were found in 52% of the patients and 12% of the controls, with the most common abnormality being left ventricular diastolic dysfunction. Echocardiographic abnormalities were markedly more common in patients with a CD4 count of <200/μL. The advanced stage of the disease, according to the WHO classification, was also associated with an increased incidence of echocardiographic abnormalities.
Cardiovascular abnormalities in the form of electrocardiogram and ECHO findings were present in 54.5% and 52% of patients, respectively. Echocardiographic findings showed significant correlation with CD4 count and WHO disease stage.
研究印度一家三级护理医院中人类免疫缺陷病毒（HIV）/获得性免疫缺陷综合征（AIDS）患者心血管异常的情况和特征。还根据世界卫生组织（WHO）分类分析了心血管异常与CD4细胞计数及疾病阶段的关联。
将总共200例HIV/AIDS患者与50名健康对照进行比较。所有患者均接受血液检查、胸部X线检查、心电图检查和超声心动图检查。
患者的平均年龄为38.66±9.22岁，男女比例为3.25:1。52%的患者和12%的对照发现有超声心动图异常，最常见的异常是左心室舒张功能障碍。CD4细胞计数<200/μL的患者中超声心动图异常明显更常见。根据WHO分类，疾病晚期也与超声心动图异常发生率增加相关。
心电图和超声心动图检查结果显示的心血管异常分别出现在54.5%和52%的患者中。超声心动图检查结果与CD4细胞计数和WHO疾病阶段显著相关。
