Ogbutor G U, Nwangwa E K, Uyagu D D
Department of Physiotherapy, Federal Medical Centre, Asaba, Nigeria.
Department of Human Physiology and Family Medicine, College of Health Sciences, Delta State University, Abraka, Delta State, Nigeria.
Niger J Clin Pract. 2019 Dec;22(12):1765-1771. doi: 10.4103/njcp.njcp_240_18.
Prehypertension highlights a category of subjects who are at high risk of developing hypertension.
This study assessed the blood pressure attenuating effect of isometric handgrip exercise in the management of prehypertension.
A total of 400 prehypertensive subject with a mean age of 40 ± 10 years and recently diagnosed as prehypertension were recruited for the study. They were randomly distributed into exercise and control groups (n = 200). The control group was placed on lifestyle modification only, while the exercise group performed a 24 consecutive days isometric hand grip exercise training at 30% maximum voluntary contraction (MVC) for 2 min each day in combination with lifestyle modification protocol.
The results show a statistically significant reduction in systolic blood pressure (SBP) and diastolic blood pressure (DBP). The exercise group had a mean reduction of 7.48 ± 0.06 and 6.41 ± 1.01 mmHg of the SBP and DBP, respectively. It was further observed that both the SBP and DBP and pulse rate significantly increased acutely within 5 min post exercise at 30% MVC with a mean value of 8.60 ± 0.20 mmHg, 7.33 ± 0.03 mmHg, and 8.24 ± 0.20 beats/min of the SBP and DBP and pulse rate, respectively. However, this increase returned to pre-exercise value within 10 min post exercises to a mean value of -0.68 + 1.64 mmHg, 1.48 ± 1.02 mmHg, and 3.00 ± 0.11 beats/min, respectively.
This study has shown that isometric handgrip exercise is effective in the attenuation of blood pressure in prehypertensive subjects especially when combined with the routinely recommended lifestyle modifications. However, caution should be taken when recommending it because of acute increase in blood pressure.
高血压前期指的是一类有患高血压高风险的人群。
本研究评估了等长握力运动在高血压前期管理中对血压的降低作用。
总共招募了400名平均年龄为40±10岁且最近被诊断为高血压前期的受试者参与本研究。他们被随机分为运动组和对照组（每组n = 200）。对照组仅进行生活方式干预，而运动组在进行生活方式干预方案的同时，每天以最大自主收缩（MVC）的30%进行2分钟的连续24天等长握力运动训练。
结果显示收缩压（SBP）和舒张压（DBP）有统计学意义的降低。运动组的SBP和DBP平均分别降低了7.48±0.06 mmHg和6.41±1.01 mmHg。进一步观察发现，在以30%MVC进行运动后5分钟内，SBP、DBP和脉搏率均显著急性升高，SBP、DBP和脉搏率的平均值分别为8.60±0.20 mmHg、7.33±0.03 mmHg和8.24±0.20次/分钟。然而，这种升高在运动后10分钟内恢复到运动前水平，平均值分别为-0.68 + 1.64 mmHg、1.48±1.02 mmHg和3.00±0.11次/分钟。
本研究表明，等长握力运动对高血压前期受试者的血压降低有效，尤其是与常规推荐的生活方式干预相结合时。然而，由于血压会急性升高，在推荐时应谨慎。
