Pallela Panduranga Naga Vijay Kumar, Ummey Shameem, Ruddaraju Lakshmi Kalyani, Gadi Satyananarayana, Cherukuri Chinmai SailajaLakshmi, Barla Sailaja, Pammi S V N
Advanced Analytical Laboratory, Andhra University, Visakhapatnam, 530003, India.
Department of Zoology, Andhra University, Visakhapatnam, 530003, India.
Heliyon. 2019 Nov 22;5(11):e02765. doi: 10.1016/j.heliyon.2019.e02765. eCollection 2019 Nov.
The aim of the work is to synthesize iron oxide (α-FeO) nanoparticles using plant extract along with evaluation of its antibacterial activity. The presence of phytochemicals in methanolic plant extract was investigated by HPTLC and LC-MS/TOF. The probable mechanism for formation of α-FeO nanoparticles in mediation with plant extract was demonstrated. The green synthesized iron oxide nanoparticles (α-FeO NPs) were characterized by using X-ray diffraction, scanning, and transmission electronic microscopy, TG-DTA, FTIR, and UV spectroscopy. The crystallite size of prepared α-FeO nanoparticles estimated via Debye-Scherrer formula and Williamson-Hall plot was around 20 nm which is in accordance with particle size in TEM images. The mediated iron-oxide nanoparticles (α-FeO NPs) hold potent antibacterial activity against various gram positive and gram negative bacteria.
这项工作的目的是使用植物提取物合成氧化铁（α-FeO）纳米颗粒，并评估其抗菌活性。通过高效薄层色谱法（HPTLC）和液相色谱-质谱/飞行时间质谱（LC-MS/TOF）研究了甲醇植物提取物中植物化学成分的存在情况。证明了植物提取物介导形成α-FeO纳米颗粒的可能机制。通过X射线衍射、扫描和透射电子显微镜、热重-差示热分析（TG-DTA）、傅里叶变换红外光谱（FTIR）和紫外光谱对绿色合成的氧化铁纳米颗粒（α-FeO NPs）进行了表征。通过德拜-谢乐公式和威廉姆森-霍尔图估算制备的α-FeO纳米颗粒的微晶尺寸约为20 nm，这与透射电子显微镜图像中的粒径一致。介导的氧化铁纳米颗粒（α-FeO NPs）对各种革兰氏阳性和革兰氏阴性细菌具有强大的抗菌活性。
