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臭氧与氯己定联合应用于慢性牙周炎患者的疗效

Effectiveness of the adjunctive use of ozone and chlorhexidine in patients with chronic periodontitis.

作者信息

Gandhi Kaveri Kranti, Cappetta Emil G, Pavaskar Rajdeep

机构信息

1Rutgers School of Dental Medicine, Newark, NJ USA.

2Department of Periodontology, Rutgers School of Dental Medicine, Newark, NJ USA.

出版信息

BDJ Open. 2019 Nov 28;5:17. doi: 10.1038/s41405-019-0025-9. eCollection 2019.

Abstract

BACKGROUND

Scaling and root planning (SRP) is the gold standard approach for treatment of chronic periodontitis but used alone it may not be effective in removing periodontal pathogens from sites where access is poor.

OBJECTIVE

To evaluate and compare the clinical and microbiological efficacy of ozone and chlorhexidine (CHX) as an adjunct to SRP in patients with chronic periodontitis.

METHODS

Twenty-five patients with generalized moderate to severe chronic periodontitis with presence of at least one site in each quadrant with a probing depth ≥5 mm were recruited. In a split mouth study design, two quadrants were randomly allocated to the SRP and ozone therapy and the remaining two quadrants to SRP and CHX therapy. Plaque index (PI), Gingival index (GI), probing depth (PD), clinical attachment loss (CAL) were assessed. Subgingival plaque samples were obtained for assessment of (Aa) and (Pg).

RESULTS

Both groups demonstrated significant intragroup reduction in PI, GI, PD, CAL, Pg count and Aa count from baseline to 3 months follow-up. There were no significant differences between two groups for any of the parameters.

CONCLUSION

Ozonated olive oil can be used as an adjunctive subgingival irrigant in patients with chronic periodontitis.

摘要

背景

龈下刮治术和根面平整术(SRP)是治疗慢性牙周炎的金标准方法,但单独使用时,对于难以到达部位的牙周病原体,可能无法有效清除。

目的

评估并比较臭氧和氯己定(CHX)作为辅助治疗手段,用于慢性牙周炎患者SRP治疗时的临床和微生物学疗效。

方法

招募25例患有广泛性中度至重度慢性牙周炎的患者,每个象限至少有一个探诊深度≥5mm的部位。采用分口研究设计,两个象限随机分配接受SRP和臭氧治疗,其余两个象限接受SRP和CHX治疗。评估菌斑指数(PI)、牙龈指数(GI)、探诊深度(PD)、临床附着丧失(CAL)。获取龈下菌斑样本,评估伴放线聚集杆菌(Aa)和牙龈卟啉单胞菌(Pg)。

结果

从基线到3个月随访,两组的PI、GI、PD、CAL、Pg计数和Aa计数在组内均显著降低。两组之间的任何参数均无显著差异。

结论

臭氧橄榄油可作为慢性牙周炎患者的辅助龈下冲洗剂。

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