位于前额的嗜酸性粒细胞增多性血管淋巴样增生症：与口服避孕药的使用是否可能存在关联？
Angiolymphoid Hyperplasia with Eosinophilia Located on the Forehead: A Possible Association with Oral Contraceptive Use?
作者信息
Theofilou Nantia-Eleni, Scolozzi Paolo, Lombardi Tommaso
机构信息
Division of Oral and Maxillofacial Surgery, Department of Surgery, University of Geneva and University Hospitals of Geneva, Geneva, Switzerland.
Oral Medicine and Oral Maxillo-Facial Pathology Unit, Division of Oral and Maxillofacial Surgery, Department of Surgery, University of Geneva and University Hospitals of Geneva, Geneva, Switzerland.
出版信息
Dermatopathology (Basel). 2019 Nov 12;6(4):225-230. doi: 10.1159/000503743. eCollection 2019 Oct-Dec.
Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon benign vasoproliferative tumor characterized by nodules, papules or plaques localized principally in the head and neck region. Histopathological examination reveals hyperplastic blood vessels lined by large endothelial cells, accompanied by an infiltrate of inflammatory cells including eosinophils. The pathogenetic mechanism remains unclear, although different theories have been proposed. Various treatment strategies have been described, but surgery remains the treatment of choice. We describe the case of a young woman with ALHE taking an oral contraceptive pill suggesting a possible etiopathogenetic relationship.
嗜酸性粒细胞增多性血管淋巴样增生（ALHE）是一种罕见的良性血管增生性肿瘤，其特征为主要位于头颈部的结节、丘疹或斑块。组织病理学检查显示由大内皮细胞衬里的增生血管，伴有包括嗜酸性粒细胞在内的炎症细胞浸润。尽管已经提出了不同的理论，但发病机制仍不清楚。已经描述了各种治疗策略，但手术仍然是首选治疗方法。我们描述了一例服用口服避孕药的患有ALHE的年轻女性病例，提示可能存在病因学关系。
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