Fabregate-Fuente M, Arbeitman C R, Cymberknop L J, Bara-Ledesma N, Arriazu-Galindo M, Martin-Fernandez L, Armentano R L, Saban-Ruiz J
Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul;2019:514-517. doi: 10.1109/EMBC.2019.8856623.
Laser Doppler flowmetry (LDF) provides a noninvasive real-time quantification of relative changes in cutaneous perfusion. Assessment of the microvascular function can provide information on the development of various cardiometabolic disorders. In recent years, non-invasive measurements have gain attention, due to the potential complications associated to invasive procedures.
To differentiate the microvascular function between subjects with cardiometabolic disorders and healthy controls.
Evaluation through LDF during post-occlusive reactive hyperemia (PORH) in patients with or without history of cardiometabolic disorders.
Peak values of microvascular flow during post-occlusive reactive hyperemia and both upload and recovery slopes were lesser in the pathological group.
A novel approach to characterize LDF during PORH was useful to differentiate patients with cardiometabolic disorders from healthy subjects.
激光多普勒血流仪（LDF）可对皮肤灌注的相对变化进行非侵入性实时量化。微血管功能评估可为各种心脏代谢紊乱的发展提供信息。近年来，由于侵入性操作存在潜在并发症，非侵入性测量受到关注。
区分患有心脏代谢紊乱的受试者与健康对照者之间的微血管功能。
对有或无心脏代谢紊乱病史的患者在阻断后反应性充血（PORH）期间通过LDF进行评估。
病理组在阻断后反应性充血期间微血管血流的峰值以及上升和恢复斜率均较小。
一种在PORH期间表征LDF的新方法有助于区分患有心脏代谢紊乱的患者与健康受试者。
