Department of Economic Informatics, University of Lodz, 90-214 Lodz, Poland.
Department of Biology and Pharmaceutical Botany, Medical University of Lodz, 90-151 Lodz, Poland.
Int J Mol Sci. 2020 Jan 19;21(2):652. doi: 10.3390/ijms21020652.
Worldwide use of electronic cigarettes has been rapidly expanding over recent years, but the long-term effect of e-cigarette vapor exposure on human health and environment is not well established; however, its mechanism of action entails the production of reactive oxygen species and trace metals, and the exacerbation of inflammation, which are associated with potential cytotoxicity and genotoxicity. The present study examines the effects of selected liquid chemicals used in e-cigarettes, such as propylene glycol/vegetable glycerin, nicotine and flavorings, on living organisms; the data collected indicates that exposure to e-cigarette liquid has potentially detrimental effects on cells in vitro, and on animals and humans in vivo. While e-liquid exposure can adversely influence the physiology of living organisms, vaping is recommended as an alternative for tobacco smoking. The study also compares the impact of e-cigarette liquid exposure and traditional cigarette smoke on organisms and the environmental impact. The environmental influence of e-cigarette use is closely connected with the emission of airborne particulate matter, suggesting the possibility of passive smoking. The obtained data provides an insight into the impact of nicotine delivery systems on living organisms and the environment.
近年来，全球范围内电子烟的使用迅速普及，但电子烟蒸汽暴露对人类健康和环境的长期影响尚未得到充分证实；然而，其作用机制涉及活性氧和痕量金属的产生，以及炎症的加剧，这与潜在的细胞毒性和遗传毒性有关。本研究考察了电子烟中使用的某些液体化学物质，如丙二醇/蔬菜甘油、尼古丁和香料，对生物体的影响；收集的数据表明，电子烟液暴露对体外细胞以及体内动物和人类具有潜在的有害影响。虽然电子烟液暴露会对生物体的生理机能产生不利影响，但仍推荐将其作为吸烟的替代选择。本研究还比较了电子烟液暴露和传统香烟烟雾对生物体和环境影响的差异。电子烟使用对环境的影响与空气传播的颗粒物排放密切相关，这提示了被动吸烟的可能性。所得数据深入了解了尼古丁输送系统对生物体和环境的影响。
