妊娠期深度表型分析在预测性和预防性医学中的应用。
Deep phenotyping during pregnancy for predictive and preventive medicine.
机构信息
Institute for Systems Biology, Seattle, WA 98109, USA.
Magee-Womens Research Institute and Departments of OBGYN and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15213, USA.
出版信息
Sci Transl Med. 2020 Jan 22;12(527). doi: 10.1126/scitranslmed.aay1059.
Abstract
Deep phenotyping during pregnancy offers an opportunity to define the antecedents of lifelong health and wellness, and to improve pregnancy outcomes.
摘要
孕期深度表型分析提供了一个机会，可以确定终生健康和健康的前因，并改善妊娠结局。
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本文引用的文献
1
Pre-eclampsia: pathophysiology and clinical implications.子痫前期：病理生理学与临床意义。
BMJ. 2019 Jul 15;366:l2381. doi: 10.1136/bmj.l2381.
2
A longitudinal big data approach for precision health.纵向大数据方法用于精准健康。
Nat Med. 2019 May;25(5):792-804. doi: 10.1038/s41591-019-0414-6. Epub 2019 May 8.
3
Genetic Predisposition Impacts Clinical Changes in a Lifestyle Coaching Program.遗传易感性对生活方式干预计划的临床变化有影响。
Sci Rep. 2019 May 2;9(1):6805. doi: 10.1038/s41598-019-43058-0.
4
Genomic and molecular characterization of preterm birth.早产的基因组和分子特征
Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5819-5827. doi: 10.1073/pnas.1716314116. Epub 2019 Mar 4.
5
Use of wearable sensors for pregnancy health and environmental monitoring: Descriptive findings from the perspective of patients and providers.可穿戴传感器在孕期健康与环境监测中的应用：患者与医护人员视角的描述性结果
Digit Health. 2019 Feb 6;5:2055207619828220. doi: 10.1177/2055207619828220. eCollection 2019 Jan-Dec.
6
Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy.人类妊娠期间免疫组学、转录组学、微生物组学、蛋白质组学和代谢组学适应性的多组学建模。
Bioinformatics. 2019 Jan 1;35(1):95-103. doi: 10.1093/bioinformatics/bty537.
7
Noninvasive blood tests for fetal development predict gestational age and preterm delivery.非侵入性胎儿发育血液检测可预测胎龄和早产。
Science. 2018 Jun 8;360(6393):1133-1136. doi: 10.1126/science.aar3819.
8
Genetic Associations with Gestational Duration and Spontaneous Preterm Birth.与妊娠期时长和自发性早产的遗传关联。
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9
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10
Effect of in utero and early-life conditions on adult health and disease.子宫内及生命早期状况对成人健康与疾病的影响。
N Engl J Med. 2008 Jul 3;359(1):61-73. doi: 10.1056/NEJMra0708473.
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