Department of Human Nutrition, University of Otago, Dunedin, New Zealand.
Microbiome Otago, University of Otago, Dunedin, New Zealand.
Eur J Clin Nutr. 2020 Sep;74(9):1362-1365. doi: 10.1038/s41430-019-0556-0. Epub 2020 Jan 22.
The gut microbiota harvests energy from indigestible plant polysaccharides, forming short-chain fatty acids (SCFAs) that are absorbed from the bowel. SCFAs provide energy-presumably after easily digested food components have been absorbed from the small intestine. Infant night waking is believed by many parents to be due to hunger. Our objective was to determine whether faecal SCFAs are associated with longer uninterrupted sleep in infants. Infants (n = 57) provided faecal samples for determining SCFAs (7 months of age), and questionnaire data for determining infant sleep (7 and 8 months). Linear regression determined associations between SCFAs-faecal acetate, propionate and butyrate-and sleep. For each 1% higher propionate at 7 months of age, the longest night sleep was 6 (95% CI: 1, 10) minutes longer at both 7 and 8 months. A higher proportion of total faecal SCFA as propionate was associated with longer uninterrupted infant sleep.
肠道微生物群从不可消化的植物多糖中获取能量，形成短链脂肪酸 (SCFA)，这些脂肪酸从肠道中被吸收。SCFA 提供能量——大概是在从小肠吸收了容易消化的食物成分之后。许多父母认为婴儿夜间醒来是因为饥饿。我们的目的是确定粪便中的 SCFA 是否与婴儿更长时间的不间断睡眠有关。研究对象是 57 名婴儿（7 个月大），他们提供粪便样本以确定 SCFA（7 个月大），并提供婴儿睡眠情况的问卷调查数据（7 个月和 8 个月）。线性回归确定了 SCFA（粪便乙酸盐、丙酸盐和丁酸盐）与睡眠之间的关联。7 个月时丙酸盐每增加 1%，7 个月和 8 个月时最长夜间睡眠时间就会延长 6 分钟（95%CI：1，10）。粪便中总 SCFA 中丙酸盐比例较高与婴儿不间断的睡眠时间较长有关。
