Health Services Vocational School of Higher Education, T.C. Istanbul Aydin University, Sefakoy Kucukcekmece, 34295, Istanbul, Turkey.
Application and Research Center for Advanced Studies, T.C. Istanbul Aydin University, Sefakoy Kucukcekmece, 34295, Istanbul, Turkey.
Environ Monit Assess. 2020 Jan 27;192(2):144. doi: 10.1007/s10661-020-8107-7.
Assessing the environmental hazard of nanoparticles can be a challenging task using various testing strategies. However, to our knowledge, no information is available about the impact of the sample preparation on the toxicity and toxicity mechanism of nanoparticles. For this aim, three sample preparation methods and their available toxicity procedures were conducted to examine the (eco) toxicity of TiO nanoparticles using bacteria model system. To detail understanding of the effect of sample preparation, the key events on the inhibition were examined by physicochemical and antioxidant responses. The findings showed that the physicochemical and toxicological behavior of the tested TiO NPs varied according to the sample preparation method.
使用各种测试策略评估纳米粒子的环境危害可能是一项具有挑战性的任务。然而，据我们所知，关于样品制备对纳米粒子毒性和毒性机制的影响的信息尚不可用。为此，采用三种样品制备方法及其现有的毒性程序，利用细菌模型系统研究了 TiO 纳米粒子的（生态）毒性。为了详细了解样品制备的影响，通过物理化学和抗氧化响应检查了抑制的关键事件。研究结果表明，测试的 TiO NPs 的物理化学和毒理学行为根据样品制备方法而有所不同。
