台湾地区儿童便秘与夜间遗尿症的相关性：基于人群的匹配病例对照研究。
Association between constipation and childhood nocturnal enuresis in Taiwan: a population-based matched case-control study.
机构信息
Department of Pediatrics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Department of Medical Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
出版信息
BMC Pediatr. 2020 Jan 28;20(1):35. doi: 10.1186/s12887-020-1939-z.
BACKGROUND
The relationship between constipation and childhood nocturnal enuresis (NE) has been previously reported; however, this relationship remains controversial. The present study aimed to evaluate the association between constipation and childhood NE.
METHODS
Data from the Longitudinal Health Insurance Database 2000 (LHID 2000) of Taiwan National Health Insurance Research Database from 2000 to 2013 were collected. A total of 2286 children were enrolled in this study: a case group of 1143 children aged 5-18 years who were diagnosed with NE (NE group) and an age- and sex-matched control group of 1143 children without NE. Conditional logistic regression and odds ratio (OR) for NE were used to examine the association between constipation and childhood NE.
RESULTS
The prevalence of NE in the case group (NE group, aged 5-18 years) was 1.03% from 2000 to 2013. The NE group had a higher percentage of constipation in 1 year before the diagnosis of NE. After stratification for sex, both boys and girls with constipation had higher OR for NE. With stratification for age, children aged 5-12 and 7-12 years had a higher OR for NE.
CONCLUSIONS
Constipation is associated with childhood NE in Taiwan, particularly in children aged 5-7 and 7-12 years.
背景
便秘与儿童夜间遗尿（NE）之间的关系先前已有报道，但该关系仍存在争议。本研究旨在评估便秘与儿童 NE 之间的关联。
方法
本研究收集了台湾全民健康保险研究数据库 2000 年（LHID 2000）2000 年至 2013 年的数据。共有 2286 名儿童纳入本研究：一组 1143 名年龄为 5-18 岁的患有 NE（NE 组）的儿童，以及一组年龄和性别匹配的 1143 名无 NE 的儿童（对照组）。采用条件逻辑回归和比值比（OR）来检验便秘与儿童 NE 之间的关联。
结果
在 2000 年至 2013 年期间，NE 组（5-18 岁）的 NE 患病率为 1.03%。NE 组在 NE 诊断前 1 年中，便秘的比例更高。按性别分层后，患有便秘的男孩和女孩患 NE 的 OR 均更高。按年龄分层后，5-12 岁和 7-12 岁的儿童患 NE 的 OR 更高。
结论
便秘与台湾儿童夜间遗尿（NE）有关，尤其是在 5-7 岁和 7-12 岁的儿童中。
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