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Editorial: Therapeutic Modulation of the Complement System: Clinical Indications and Emerging Drug Leads.

作者信息

Mastellos Dimitrios C, Reis Edimara S, Lambris John D

机构信息

National Center for Scientific Research "Demokritos", Athens, Greece.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

出版信息

Front Immunol. 2020 Jan 9;10:3029. doi: 10.3389/fimmu.2019.03029. eCollection 2019.

Abstract
摘要

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本文引用的文献

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Context-dependent roles of complement in cancer.补体在癌症中的语境相关作用。
Nat Rev Cancer. 2019 Dec;19(12):698-715. doi: 10.1038/s41568-019-0210-0. Epub 2019 Oct 30.
3
Clinical promise of next-generation complement therapeutics.下一代补体治疗药物的临床前景。
Nat Rev Drug Discov. 2019 Sep;18(9):707-729. doi: 10.1038/s41573-019-0031-6. Epub 2019 Jul 19.
5
Developments in anti-complement therapy; from disease to clinical trial.抗补体治疗的进展;从疾病到临床试验。
Mol Immunol. 2018 Oct;102:89-119. doi: 10.1016/j.molimm.2018.06.008. Epub 2018 Aug 16.
6
The renaissance of complement therapeutics.补体疗法的复兴。
Nat Rev Nephrol. 2018 Jan;14(1):26-47. doi: 10.1038/nrneph.2017.156. Epub 2017 Dec 4.
7
Novel mechanisms and functions of complement.补体的新机制与功能
Nat Immunol. 2017 Nov 16;18(12):1288-1298. doi: 10.1038/ni.3858.
8
Complement in cancer: untangling an intricate relationship.补体系统在癌症中的作用:揭示复杂关系。
Nat Rev Immunol. 2018 Jan;18(1):5-18. doi: 10.1038/nri.2017.97. Epub 2017 Sep 18.
9
Complement in disease: a defence system turning offensive.补体系统在疾病中的作用:防御系统转为进攻。
Nat Rev Nephrol. 2016 Jul;12(7):383-401. doi: 10.1038/nrneph.2016.70. Epub 2016 May 23.
10
Complement, a target for therapy in inflammatory and degenerative diseases.补体,炎症和退行性疾病的治疗靶点。
Nat Rev Drug Discov. 2015 Dec;14(12):857-77. doi: 10.1038/nrd4657. Epub 2015 Oct 23.

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