Department of Neurosurgery, Northwestern University, Chicago, Illinois, USA.
Department of Neurosurgery, Northwestern University, Chicago, Illinois, USA; Department of Orthopaedic Surgery, Northwestern University, Chicago, Illinois, USA.
World Neurosurg. 2020 Jun;138:e42-e51. doi: 10.1016/j.wneu.2020.01.154. Epub 2020 Jan 28.
Anterior cervical discectomy and fusion (ACDF) is the most common procedure for the treatment of degenerative cervical conditions. The objective of this study is to determine time-dependent trends in patient outcomes following ACDF for degenerative disease from 2006 to 2016.
We used the National Surgical Quality Improvement Program (NSQIP) database to retrospectively review all patients who underwent elective ACDF between 2006 and 2016. A descriptive statistical analysis followed by time trend analysis was performed on demographics, comorbidities, perioperative, and outcome variables. Primary outcomes were reoperation and readmission rates. Secondary outcomes were medical and surgical complications reported within 30 days of operation.
A total of 36,854 patients underwent elective ACDF from the 2006 to 2016 NSQIP database. Mean age increased from 48.19 years [standard error: 1.49] in 2006 to 54.08 years [standard error: 0.12] in 2016 (P < 0.001). There was a significantly greater number of outpatient procedures from 2012 to 2016 (P < 0.001). The proportion of patients with American Society of Anesthesiologists classes 3/4 significantly increased over time (P < 0.001, P < 0.001, P = 0.005, respectively). Readmission risk, first documented in NSQIP in 2011, increased over time from 2011 to 2016 (P < 0.001). Unplanned reoperations have remained consistent at about 1.4%. Postoperative complications varied over time with no discernable patterns or trends.
Since the establishment of the NSQIP database, there have been no considerable improvements in reoperation or postoperative complication rates based on available data, however, there have been increased rates of readmission. Changes in data collection and an aging patient population with greater burden of comorbidities could confound these trends.
颈椎前路椎间盘切除融合术(ACDF)是治疗退行性颈椎疾病最常见的手术。本研究旨在确定 2006 年至 2016 年期间,退行性疾病患者接受 ACDF 治疗后的时间依赖性结果趋势。
我们使用国家手术质量改进计划(NSQIP)数据库回顾性分析了 2006 年至 2016 年间接受择期 ACDF 的所有患者。对人口统计学、合并症、围手术期和结果变量进行描述性统计分析和时间趋势分析。主要结果为再次手术和再入院率。次要结果为术后 30 天内报告的医疗和手术并发症。
共有 36854 例患者从 2006 年至 2016 年的 NSQIP 数据库中接受了择期 ACDF。平均年龄从 2006 年的 48.19 岁(标准误差:1.49)增加到 2016 年的 54.08 岁(标准误差:0.12)(P < 0.001)。从 2012 年到 2016 年,门诊手术的数量显著增加(P < 0.001)。患有美国麻醉医师协会(ASA)3/4 级疾病的患者比例随着时间的推移显著增加(P < 0.001,P < 0.001,P = 0.005)。2011 年首次在 NSQIP 中记录的再入院风险在 2011 年至 2016 年间呈上升趋势(P < 0.001)。计划外再次手术率一直保持在 1.4%左右。术后并发症随时间变化,无明显模式或趋势。
根据现有数据,自 NSQIP 数据库建立以来,再次手术或术后并发症发生率没有明显改善,但是再入院率有所增加。数据收集的变化和患有更多合并症的老龄化患者人群可能会使这些趋势复杂化。