Long Alicia, Nolen-Walston Rose
Department of Clinical Studies, New Bolton Center, 382 West Street Road, Kennett Square, PA 19348, USA.
Department of Clinical Studies, New Bolton Center, 382 West Street Road, Kennett Square, PA 19348, USA.
Vet Clin North Am Equine Pract. 2020 Apr;36(1):147-160. doi: 10.1016/j.cveq.2019.12.005. Epub 2020 Jan 30.
Serum amyloid A (SAA) is a marker of inflammation and infection in the horse that can be assessed in the field, with rapid and marked changes seen following initiation of an inflammatory stimulus. This quality of SAA also makes its clinical use challenging, because even small inflammatory conditions can cause large changes in SAA levels. Review of the current literature provides guidelines for responses of SAA to various conditions, which can be applied to specific clinical cases. The practitioner is encouraged to use SAA in conjunction with physical examination and other diagnostic modalities to guide treatment and monitor case progression.
血清淀粉样蛋白A（SAA）是马匹炎症和感染的标志物，可在现场进行评估，在炎症刺激开始后会出现快速且显著的变化。SAA的这一特性也使其临床应用具有挑战性，因为即使是轻微的炎症状态也会导致SAA水平发生很大变化。对当前文献的回顾提供了SAA对各种情况反应的指导原则，可应用于特定临床病例。鼓励从业者将SAA与体格检查及其他诊断方法结合使用，以指导治疗并监测病例进展。
