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妇科癌症与不孕症中的精准个性化医疗

Precise Personalized Medicine in Gynecology Cancer and Infertility.

作者信息

Zhang Pu-Yao, Yu Yang

机构信息

Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China.

Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Peking University Third Hospital, Beijing, China.

出版信息

Front Cell Dev Biol. 2020 Jan 17;7:382. doi: 10.3389/fcell.2019.00382. eCollection 2019.

Abstract

Since the conception of precision medicine has been put forward in oncology, this idea has been popularized and applied in many specialties. Significant progress has been made toward personalizing the entire process, including diagnosis, treatment planning, and embryo identification, and combining large-scale genetic information data and knowledge discovery can offer better prospects in reproductive medicine. This work reviews the application of precision medicine and possibilities in reproductive medicine and gynecologic cancer diagnosis and treatment. The limitations and challenges of precision medicine in this area remain to be discussed.

摘要

自从精准医学的概念在肿瘤学中被提出以来,这一理念已在许多专科中得到推广和应用。在包括诊断、治疗规划和胚胎识别在内的整个过程的个性化方面已取得重大进展,并且将大规模遗传信息数据与知识发现相结合能够在生殖医学领域提供更好的前景。本文综述了精准医学在生殖医学以及妇科癌症诊断与治疗中的应用及可能性。精准医学在该领域的局限性和挑战仍有待探讨。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cad/6978655/b3bb25b6b0ec/fcell-07-00382-g002.jpg

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