Department of Hepatic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, HeFei, 230001, China.
Anhui Province Key Laboratory of Hepatopancreatobiliary Surgery, HeFei, 230001, China.
Int J Biol Sci. 2020 Jan 1;16(3):365-373. doi: 10.7150/ijbs.39387. eCollection 2020.
In the past 20 years, the concept of surgery has undergone profound changes. Surgical practice has shifted from emphasizing the complete elimination of lesions to achieving optimal rehabilitation in patients. Collaborative optimization of surgery consists of three core elements, removal of lesions, organ protection and injury close monitoring, and controlled surgical intervention. As a result, the traditional surgical paradigm has quietly transformed into a modern precision surgical paradigm. In this review, we summarized the latest breakthroughs and applications of precision medicine in liver surgery. In addition, we also outlined the progresses that have been made in precision liver surgery, the opportunities and challenges that may encountered in the future.
在过去的 20 年中，外科手术的概念发生了深刻的变化。外科实践已从强调彻底消除病变转变为实现患者的最佳康复。协作优化手术由三个核心要素组成，即病变切除、器官保护和损伤密切监测以及控制性手术干预。因此，传统的外科范式已悄然转变为现代精准外科范式。在这篇综述中，我们总结了精准医学在肝外科中的最新突破和应用。此外，我们还概述了精准肝外科的进展，以及未来可能遇到的机遇和挑战。
