• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

阻生第三磨牙手术拔除后下颌第二磨牙远中牙周袋的治疗及富含白细胞的纤维蛋白的应用:一项半口随机临床试验

Treatment of periodontal pockets at the distal aspect of mandibular second molar after surgical removal of impacted third molar and application of L-PRF: a split-mouth randomized clinical trial.

作者信息

Gasparro Roberta, Sammartino Gilberto, Mariniello Mauro, di Lauro Alessandro Espedito, Spagnuolo Gianrico, Marenzi Gaetano

出版信息

Quintessence Int. 2020;51(3):204-211. doi: 10.3290/j.qi.a43947.

DOI:10.3290/j.qi.a43947
PMID:32020130
Abstract

OBJECTIVES

Presence of clinical attachment loss on the distal aspect to the second molar may be associated with malposition of the third molar. The aim of this study was to evaluate the reduction of clinical attachment loss at the distal aspect of the second molar after third molar extraction and application of leukocyte- and platelet-rich fibrin (L-PRF).

METHOD AND MATERIALS

Eighteen subjects with a clinical attachment loss on the distal site to the second molar associated with impacted third molar in both sides of the jaw were recruited for the study. For each subject the teeth were randomly allocated in test and control groups. After surgical removal of the impacted third molar, the L-PRF was inserted in the fresh alveolar socket of test sites; in the control sites no graft was inserted after extraction. Full-mouth plaque score, full-mouth bleeding score, clinical attachment level (CAL), probing depth, and gingival recession were assessed at baseline and 6 months later.

RESULTS

After 6 months, mean CAL change was 1.99 ± 1.18 mm in the test group and 1.15 ± 1.01 mm in the control group; probing depth change was 1.33 ± 0.87 mm in the test group and 0.50 ± 0.63 mm in the control group. Statistically significant differences (P < .05) were observed between groups in terms of CAL and probing depth changes. No differences were found in gingival recession changes.

CONCLUSION

Within the limits of the present study, the sites treated by means of application of L-PRF after impacted third molar extraction showed better results in terms of CAL gain and probing depth reduction when compared with control sites.

摘要

目的

第二磨牙远中临床附着丧失的存在可能与第三磨牙的错位有关。本研究的目的是评估拔除第三磨牙并应用富白细胞和血小板纤维蛋白(L-PRF)后,第二磨牙远中临床附着丧失的减少情况。

方法和材料

招募了18名双侧下颌第二磨牙远中部位存在与阻生第三磨牙相关的临床附着丧失的受试者进行研究。对于每个受试者,牙齿被随机分配到试验组和对照组。在手术拔除阻生第三磨牙后,将L-PRF插入试验部位的新鲜牙槽窝;对照组拔牙后不植入移植物。在基线和6个月后评估全口菌斑评分、全口出血评分、临床附着水平(CAL)、探诊深度和牙龈退缩情况。

结果

6个月后,试验组平均CAL变化为1.99±1.18mm,对照组为1.15±1.01mm;试验组探诊深度变化为1.33±0.87mm,对照组为0.50±0.63mm。在CAL和探诊深度变化方面,两组间观察到统计学显著差异(P<.05)。牙龈退缩变化未发现差异。

结论

在本研究的范围内,与对照组相比,阻生第三磨牙拔除后应用L-PRF治疗的部位在CAL增加和探诊深度减少方面显示出更好的结果。

相似文献

1
Treatment of periodontal pockets at the distal aspect of mandibular second molar after surgical removal of impacted third molar and application of L-PRF: a split-mouth randomized clinical trial.阻生第三磨牙手术拔除后下颌第二磨牙远中牙周袋的治疗及富含白细胞的纤维蛋白的应用:一项半口随机临床试验
Quintessence Int. 2020;51(3):204-211. doi: 10.3290/j.qi.a43947.
2
Effect of Advanced Platelet-rich Fibrin on Wound Healing after Third Molar Extraction: A Split-mouth Randomized Double-blind Study.富血小板纤维蛋白对第三磨牙拔除术后伤口愈合的影响:一项双盲随机对照研究。
J Contemp Dent Pract. 2019 Oct 1;20(10):1164-1170.
3
The effect of dental pulp stem cells and L-PRF when placed into the extraction sockets of impacted mandibular third molars on the periodontal status of adjacent second molars: a split-mouth, randomized, controlled clinical trial.将牙髓干细胞和富血小板纤维蛋白置于下颌阻生第三磨牙拔牙窝内对相邻第二磨牙牙周状况的影响:一项双侧对照、随机、对照临床试验。
Oral Maxillofac Surg. 2023 Mar;27(1):59-68. doi: 10.1007/s10006-022-01045-2. Epub 2022 Feb 9.
4
Does grafting of third molar extraction sockets enhance periodontal measures in 30- to 35-year-old patients?在30至35岁患者中,第三磨牙拔牙窝植骨是否能改善牙周指标?
J Oral Maxillofac Surg. 2012 Apr;70(4):757-64. doi: 10.1016/j.joms.2011.09.010. Epub 2011 Dec 16.
5
Comparison of the effect of advanced platelet-rich fibrin and leukocyte- and platelet-rich fibrin on outcomes after removal of impacted mandibular third molar: A randomized split-mouth study.富血小板纤维蛋白与富白细胞和血小板纤维蛋白对下颌阻生第三磨牙拔除术后疗效的比较:一项随机双盲研究。
Niger J Clin Pract. 2019 Apr;22(4):546-552. doi: 10.4103/njcp.njcp_473_18.
6
Residual periodontal defects distal to the mandibular second molar 6-36 months after impacted third molar extraction.下颌第三磨牙拔除6 - 36个月后,下颌第二磨牙远中残留的牙周缺损。
J Clin Periodontol. 2002 Nov;29(11):1004-11. doi: 10.1034/j.1600-051x.2002.291105.x.
7
Influence of leukocyte- and platelet-rich fibrin (L-PRF) on the outcomes of impacted mandibular third molar removal surgery: A split-mouth randomized clinical trial.富白细胞和血小板纤维蛋白(L-PRF)对下颌阻生第三磨牙拔除手术结果的影响:一项双侧对照随机临床试验。
Quintessence Int. 2018;49(5):377-388. doi: 10.3290/j.qi.a40113.
8
Effects of lower third molar extraction on attachment level and alveolar bone height of the adjacent second molar.下颌第三磨牙拔除对相邻第二磨牙附着水平和牙槽骨高度的影响。
Int J Oral Maxillofac Surg. 2005 Oct;34(7):756-60. doi: 10.1016/j.ijom.2005.02.006.
9
Use of resorbable membranes in periodontal defects treatment after extraction of impacted mandibular third molars.可吸收膜在下颌阻生第三磨牙拔除后牙周缺损治疗中的应用。
Minerva Stomatol. 2007 Oct;56(10):497-508.
10
Evaluation of treatment outcome after impacted mandibular third molar surgery with the use of autologous platelet-rich fibrin: a randomized controlled clinical study.使用自体富血小板纤维蛋白评估下颌阻生第三磨牙手术后的治疗效果:一项随机对照临床研究。
J Oral Maxillofac Surg. 2015 Jun;73(6):1042-9. doi: 10.1016/j.joms.2014.11.013. Epub 2014 Dec 13.

引用本文的文献

1
The efficacy of platelet-rich fibrin (PRF) in post-extraction hard and soft tissue healing and associated complications: a systematic review and meta-analysis of split-mouth randomized clinical trials.富血小板纤维蛋白(PRF)在拔牙后软硬组织愈合及相关并发症中的疗效:一项对分口随机临床试验的系统评价和荟萃分析。
BMC Oral Health. 2025 May 31;25(1):869. doi: 10.1186/s12903-025-06238-1.
2
The Role of Platelet Concentrates and Growth Factors in Facial Rejuvenation: A Systematic Review with Case Series.血小板浓缩物和生长因子在面部年轻化中的作用:一项病例系列的系统评价
Medicina (Kaunas). 2025 Jan 7;61(1):84. doi: 10.3390/medicina61010084.
3
Management of Oro-Antral Communication: A Systemic Review of Diagnostic and Therapeutic Strategies.
口腔上颌窦瘘的管理:诊断和治疗策略的系统评价
Diagnostics (Basel). 2025 Jan 16;15(2):194. doi: 10.3390/diagnostics15020194.
4
Using platelet concentrates to treat maxillofacial tissue lesions.使用血小板浓缩物治疗颌面组织损伤。
Front Bioeng Biotechnol. 2025 Jan 7;12:1523225. doi: 10.3389/fbioe.2024.1523225. eCollection 2024.
5
Effectiveness of platelet-rich fibrin in third molar extractions: a randomized controlled split-mouth study.富血小板纤维蛋白在第三磨牙拔除术中的有效性:一项随机对照分口研究。
Clin Oral Investig. 2024 Oct 29;28(11):615. doi: 10.1007/s00784-024-06002-9.
6
Peri-Implantitis-Associated Microbiota before and after Peri-Implantitis Treatment, the Biofilm "Competitive Balancing" Effect: A Systematic Review of Randomized Controlled Trials.种植体周围炎治疗前后与种植体周围炎相关的微生物群,生物膜的“竞争平衡”效应:一项随机对照试验的系统评价
Microorganisms. 2024 Sep 28;12(10):1965. doi: 10.3390/microorganisms12101965.
7
Customized 3D-Printed Mesh, Membrane, Bone Substitute, and Dental Implant Applied to Guided Bone Regeneration in Oral Implantology: A Narrative Review.定制3D打印网片、膜、骨替代物和牙种植体在口腔种植学引导骨再生中的应用:一项叙述性综述
Dent J (Basel). 2024 Sep 25;12(10):303. doi: 10.3390/dj12100303.
8
The Role of Autologous Platelet Concentrates as a Local Antibiotic Delivery System: A Systematic Scoping Review.自体血小板浓缩物作为局部抗生素递送系统的作用:一项系统综述。
Antibiotics (Basel). 2024 Sep 6;13(9):856. doi: 10.3390/antibiotics13090856.
9
Periodontitis in Psoriatic Patients: Epidemiological Insights and Putative Etiopathogenic Links.银屑病患者的牙周炎:流行病学见解及潜在病因联系
Epidemiologia (Basel). 2024 Jul 26;5(3):479-498. doi: 10.3390/epidemiologia5030033.
10
Comparison of immediate vs. delayed guided tissue regeneration in Infrabony defect of second molars after adjacent third molar extraction: a retrospective study.相邻第三磨牙拔除后第二磨牙骨下袋缺损即刻与延迟引导组织再生的比较:一项回顾性研究。
BMC Oral Health. 2024 Jul 23;24(1):830. doi: 10.1186/s12903-024-04591-1.