Yan Wenying, Hu Hongmei, Tang Biao
Department of Gynecology, Wangjiang Hospital, Sichuan University, China, No. 24, South Section of First Ring Road, Chengdu City, Sichuan Province, China.
Department of Gynecology, Sichuan Maternal and Child Health Hospital, No. 290 Shayan West Second Street, Jinyang Road, Chengdu City, Sichuan Province, China.
Eur J Obstet Gynecol Reprod Biol X. 2019 Jun 15;5:100067. doi: 10.1016/j.eurox.2019.100067. eCollection 2020 Jan.
Endometriosis is a common gynecological disease. However, the etiology of endometriosis is still unclear, and current theories cannot fully elaborate its specific pathogenesis. Recently, some research has suggested that the occurrence and development of endometriosis may be related to genetics. Long-chain non-coding RNA (lncRNAs) is a kind of non-protein-coding RNA molecule with a length of 200-100,000 bp. With complex biological functions, lncRNAs play an important role in the normal development of individuals and the progression of various diseases, and lncRNAs have become an important field of medical research in recent years. This paper mainly illustrates the research progress on lncRNAs as they relate to endometriosis. We also provide some ideas for exploring the pathogenesis of endometriosis.
子宫内膜异位症是一种常见的妇科疾病。然而，子宫内膜异位症的病因仍不清楚，目前的理论无法完全阐明其具体发病机制。最近，一些研究表明，子宫内膜异位症的发生和发展可能与遗传学有关。长链非编码RNA（lncRNAs）是一种长度为200-100,000碱基对的非蛋白质编码RNA分子。lncRNAs具有复杂的生物学功能，在个体的正常发育和各种疾病的进展中发挥着重要作用，并且lncRNAs近年来已成为医学研究的一个重要领域。本文主要阐述了lncRNAs与子宫内膜异位症相关的研究进展。我们还为探索子宫内膜异位症的发病机制提供了一些思路。
