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血管运动驱动 Aβ 从大脑沿动脉周围间隙排出。

Vasomotion Drives Periarterial Drainage of Aβ from the Brain.

机构信息

University of Southampton, Southampton, UK.

University of Southampton, Southampton, UK; Roche Pharma Research and Early Development (pRED), Pharmaceutical Sciences, Roche Innovation Center Basel, Basel, Switzerland.

出版信息

Neuron. 2020 Feb 5;105(3):400-401. doi: 10.1016/j.neuron.2020.01.011.

DOI:10.1016/j.neuron.2020.01.011
PMID:32027828
Abstract

In this issue of Neuron, van Veluw et al. (2020) show that elimination of solutes from the brain along arterial walls is driven by low-frequency arteriolar oscillations and suggest that age-related reduction of this vasomotion may contribute to impaired clearance of Aβ.

摘要

在本期《神经元》杂志上,van Veluw 等人(2020 年)表明,大脑中溶质沿着动脉壁的清除是由低频的小动脉波动驱动的,并提出这种血管运动的年龄相关性降低可能导致 Aβ 清除能力受损。

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