Department of Biotechnology, Delhi Technological University, Shahbad Daulatpur, Delhi, 110042, India.
Department of Applied Chemistry, Delhi Technological University, Shahbad Daulatpur, Delhi, 110042, India.
Biotechnol J. 2020 May;15(5):e1900279. doi: 10.1002/biot.201900279. Epub 2020 Feb 24.
One of the major challenges for scientists and engineers today is to develop technologies for the improvement of human health in both developed and developing countries. However, the need for cost-effective, high-performance diagnostic techniques is very crucial for providing accessible, affordable, and high-quality healthcare devices. In this context, microfluidic-based devices (MFDs) offer powerful platforms for automation and integration of complex tasks onto a single chip. The distinct advantage of MFDs lies in precise control of the sample quantities and flow rate of samples and reagents that enable quantification and detection of analytes with high resolution and sensitivity. With these excellent properties, microfluidics (MFs) have been used for various applications in healthcare, along with other biological and medical areas. This review focuses on the emerging demands of MFs in different fields such as biomedical diagnostics, environmental analysis, food and agriculture research, etc., in the last three or so years. It also aims to reveal new opportunities in these areas and future prospects of commercial MFDs.
如今，科学家和工程师面临的主要挑战之一是开发技术，以提高发达国家和发展中国家的人类健康水平。然而，对于提供可及、负担得起和高质量的医疗设备而言，具有成本效益、高性能的诊断技术的需求至关重要。在这种情况下，基于微流控的设备（MFD）为自动化和将复杂任务集成到单个芯片上提供了强大的平台。MFD 的显著优势在于能够精确控制样品数量和样品及试剂的流速，从而实现高分辨率和高灵敏度的分析物定量和检测。凭借这些卓越的性能，微流控（MF）已在医疗保健以及其他生物和医学领域的各种应用中得到了广泛应用。本综述重点介绍了过去三年左右 MF 在生物医学诊断、环境分析、食品和农业研究等不同领域的新兴需求，同时也揭示了这些领域的新机遇和商业 MFD 的未来前景。
