Wang Yue, Dong Qian, Chen Yu-Dan, Hu Wen-Li, Zhao Li
Department of Neurology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China.
Department of Neurobiology and Center of Stroke, Beijing Institute for Brain Disorders, Capital Medical University, Beijing, China.
J Int Med Res. 2020 Feb;48(2):300060520903215. doi: 10.1177/0300060520903215.
Epstein–Barr virus (EBV) is a member of the herpesvirus family, which infects most of the world’s population. EBV infection usually occurs asymptomatically. However, there are subsets of the population, such as juveniles and immunocompromised patients, among whom EBV may manifest symptomatically. In some cases, symptomatology involves the central nervous system. One such manifestation of EBV is meningitis. We report a unique case of EBV infectious meningitis in an immunocompetent adult female patient who showed unconventional clinical features. These features included afternoon fever, high intracranial pressure, low cerebrospinal fluid glucose levels, and an absence of blood monocytosis. Because this case involved a unique symptomatology, our findings broaden the symptom profile of EBV infection as presently understood.
爱泼斯坦-巴尔病毒（EBV）是疱疹病毒家族的一员，它感染了世界上大多数人口。EBV感染通常无症状。然而，在人群中有一些亚组，如青少年和免疫功能低下的患者，EBV可能会出现症状。在某些情况下，症状涉及中枢神经系统。EBV的一种这样的表现是脑膜炎。我们报告了一例免疫功能正常的成年女性患者发生的EBV感染性脑膜炎的独特病例，该患者表现出非传统的临床特征。这些特征包括午后发热、高颅内压、低脑脊液葡萄糖水平以及无血单核细胞增多。由于该病例涉及独特的症状，我们的发现拓宽了目前所理解的EBV感染的症状谱。
