从气球花（Platycodon grandiflorus）中分离到的一种新型α内罗病毒的特性研究。
Characterisation of a novel alphaendornavirus isolated from balloon flower (Platycodon grandiflorus).
机构信息
Anhui Academy of Agricultural Sciences, Hefei, 230031, Anhui, China.
出版信息
Arch Virol. 2020 Apr;165(4):1023-1026. doi: 10.1007/s00705-020-04550-5. Epub 2020 Feb 13.
The complete genome sequence of a new virus, provisionally named "balloon flower endornavirus" (BfEV), was determined following virus isolation from leaves of a balloon flower (Platycodon grandiflorum) exhibiting severe leaf shrinkage disease in Anhui Province, China. The 15,180-nucleotide genome sequence of BfEV shares 40.52% amino acid (aa) sequence identity and 98% coverage with the polyprotein of Helianthus annuus endornavirus (HaEV). The open reading frame (ORF) encodes a deduced 4,887-aa polyprotein with RNA-dependent RNA polymerase (RdRp), viral helicase (Hel) and glycosyltransferase (GT) domains. Phylogenetic analysis of the amino acid sequences of RdRp places BfEV alongside members of the genus Alphaendornavirus in the family Endornaviridae. To our knowledge, this is the first report of a complete genome sequence of a novel alphaendornavirus identified in balloon flower.
一种新病毒的全基因组序列，暂时命名为“气球花内源性病毒”（BfEV），是在中国安徽省表现出严重叶片皱缩病的气球花叶片中分离病毒后确定的。BfEV 的 15180 个核苷酸基因组序列与向日葵内源性病毒（HaEV）的多蛋白具有 40.52%的氨基酸（aa）序列同一性和 98%的覆盖率。开放阅读框（ORF）编码一个推定的 4887 个氨基酸的多蛋白，具有 RNA 依赖性 RNA 聚合酶（RdRp）、病毒解旋酶（Hel）和糖基转移酶（GT）结构域。RdRp 氨基酸序列的系统发育分析将 BfEV 与 Endornaviridae 家族的 Alphaendornavirus 属成员放在一起。据我们所知，这是首次在气球花中鉴定到新型 Alphaendornavirus 的完整基因组序列。
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