• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

传统环境下的卡瓦饮用:对认知功能影响的理解。

Kava drinking in traditional settings: Towards understanding effects on cognitive function.

机构信息

Te Huataki Waiora School of Health, The University of Waikato, Hamilton, New Zealand.

School of Engineering, The Faculty of Science & Engineering, The University of Waikato, Hamilton, New Zealand.

出版信息

Hum Psychopharmacol. 2020 Mar;35(2):e2725. doi: 10.1002/hup.2725. Epub 2020 Feb 16.

DOI:10.1002/hup.2725
PMID:32064691
Abstract

BACKGROUND

Kava drinking is a tradition among Pacific Island people, although growing in popularity with other ethnicities. However, drinking substantial quantities of kava has raised concerns regarding physical manifestations of slow response and lack of precision in bodily control. These impairments can have significant consequences when after consuming large volumes of kava an individual makes a choice to drive.

AIMS

The objective of this study was to measure selected cognitive functions following high traditionally consumed kava volumes (greater than 2,000 mg of kavalactones) aimed at identifying potential risks for kava drink-drivers.

METHODS

The reaction and divided attention of 20 control participants was assessed against 20 active kava-drinking participants during and following a 6-hr kava session in a "naturalised" setting. Assessment measures were drawn from Vienna Test System-Traffic's test battery.

RESULTS/OUTCOMES: Results showed no statistical significant difference between control and active participants at any measurement point over a 6-hr testing period regardless that the movements and speech of the active participants were observed to slow as the test session and kava consumption progressed.

CONCLUSION

Inconsistencies between test results and observations during testing and by road policing officers demonstrate an urgent need for more research in this field.

摘要

背景

卡瓦酒是太平洋岛屿民族的传统饮品,尽管其他族裔也越来越喜欢喝卡瓦酒。然而,大量饮用卡瓦酒引起了人们对身体反应缓慢和身体控制缺乏精度等身体表现的关注。当一个人在大量饮用卡瓦酒后选择开车时,这些损伤可能会产生重大后果。

目的

本研究的目的是测量高传统卡瓦酒摄入量(超过 2000 毫克卡瓦内酯)后选定的认知功能,以确定卡瓦酒驾驶者的潜在风险。

方法

在“自然化”环境中,对 20 名对照参与者和 20 名活跃的卡瓦酒饮用者进行反应和分散注意力的评估,在 6 小时的卡瓦酒疗程中进行评估。评估措施取自维也纳测试系统-交通的测试套件。

结果/结果:无论在 6 小时的测试期间,观察到活跃参与者的动作和言语随着测试和卡瓦酒的消耗而变慢,结果显示在任何测量点上,对照组和活跃组之间都没有统计学上的显著差异。

结论

测试结果与测试期间和道路警察观察到的结果不一致,这表明在这一领域急需进行更多的研究。

相似文献

1
Kava drinking in traditional settings: Towards understanding effects on cognitive function.传统环境下的卡瓦饮用:对认知功能影响的理解。
Hum Psychopharmacol. 2020 Mar;35(2):e2725. doi: 10.1002/hup.2725. Epub 2020 Feb 16.
2
The impact of traditional kava (Piper methysticum) use on cognition: Implications for driver fitness.传统卡瓦( Piper methysticum )使用对认知的影响:对驾驶员健康的影响。
J Ethnopharmacol. 2022 Jun 12;291:115080. doi: 10.1016/j.jep.2022.115080. Epub 2022 Feb 11.
3
Is driving under the influence of kava associated with motor vehicle crashes? A systematic review of the epidemiological literature.饮用卡瓦酒后驾车是否与机动车碰撞事故有关?对流行病学文献的系统评价。
Aust N Z J Public Health. 2015 Oct;39(5):495-9. doi: 10.1111/1753-6405.12435. Epub 2015 Sep 3.
4
Cases of Kava Impairment in Iowa Drivers.爱荷华州司机因卡瓦酒受损的案例。
J Forensic Sci. 2019 Nov;64(6):1943-1949. doi: 10.1111/1556-4029.14130. Epub 2019 Jul 15.
5
Does a medicinal dose of kava impair driving? A randomized, placebo-controlled, double-blind study.药用剂量的卡瓦是否会影响驾驶?一项随机、安慰剂对照、双盲研究。
Traffic Inj Prev. 2013;14(1):13-7. doi: 10.1080/15389588.2012.682233.
6
Driving following Kava Use and Road Traffic Injuries: A Population-Based Case-Control Study in Fiji (TRIP 14).卡瓦使用后驾车与道路交通伤害:斐济一项基于人群的病例对照研究(TRIP 14)
PLoS One. 2016 Mar 1;11(3):e0149719. doi: 10.1371/journal.pone.0149719. eCollection 2016.
7
Saccade and cognitive impairment associated with kava intoxication.与卡瓦中毒相关的扫视和认知障碍。
Hum Psychopharmacol. 2003 Oct;18(7):525-33. doi: 10.1002/hup.532.
8
Saccade and cognitive function in chronic kava users.慢性卡瓦使用者的扫视与认知功能。
Neuropsychopharmacology. 2003 Feb;28(2):389-96. doi: 10.1038/sj.npp.1300052.
9
Kava hepatotoxicity solution: A six-point plan for new kava standardization.卡瓦肝毒性解决方案:新卡瓦标准化六点计划。
Phytomedicine. 2011 Jan 15;18(2-3):96-103. doi: 10.1016/j.phymed.2010.10.002. Epub 2010 Nov 26.
10
The neurobehavioural effects of kava.卡瓦的神经行为效应。
Aust N Z J Psychiatry. 2002 Oct;36(5):657-62. doi: 10.1046/j.1440-1614.2002.01027.x.

引用本文的文献

1
Global Perspectives on Kava: A Narrative Systematic Review of the Health Effects, Economic and Social Impacts and Policy Considerations.卡瓦的全球视角:关于健康影响、经济和社会影响及政策考量的叙述性系统综述
Drug Alcohol Rev. 2025 Sep;44(6):1601-1640. doi: 10.1111/dar.14080. Epub 2025 Jun 25.
2
Innovating through tradition: kava- as a culturally aligned medico-behavioral therapeutic approach to amelioration of PTSD symptoms.通过传统进行创新:卡瓦——一种与文化相契合的医学行为治疗方法,用于改善创伤后应激障碍症状。
Front Psychol. 2025 May 27;16:1460731. doi: 10.3389/fpsyg.2025.1460731. eCollection 2025.
3
The potential of AB-free kava in enabling tobacco cessation via management of abstinence-related stress and insomnia: study protocol for a randomized clinical trial.
无AB成分的卡瓦通过管理与戒烟相关的压力和失眠来帮助戒烟的潜力:一项随机临床试验的研究方案
BMC Complement Med Ther. 2024 Dec 21;24(1):422. doi: 10.1186/s12906-024-04722-9.
4
Innovative strategies and challenges mosquito-borne disease control amidst climate change.气候变化背景下蚊媒疾病控制的创新策略与挑战
Front Microbiol. 2024 Nov 5;15:1488106. doi: 10.3389/fmicb.2024.1488106. eCollection 2024.
5
Flavokavains A- and B-Free Kava Enhances Resilience against the Adverse Health Effects of Tobacco Smoke in Mice.不含黄酮类卡瓦因A和B的卡瓦增强小鼠对烟草烟雾有害健康影响的抵抗力。
ACS Pharmacol Transl Sci. 2024 Oct 2;7(11):3502-3517. doi: 10.1021/acsptsci.4c00415. eCollection 2024 Nov 8.
6
Kavalactone Kawain Impedes Urothelial Tumorigenesis in UPII-Mutant Ha-Ras Mice via Inhibition of mTOR Signaling and Alteration of Cancer Metabolism.卡瓦内酯卡瓦因通过抑制 mTOR 信号和改变癌症代谢来阻碍 UPII 突变 Ha-Ras 小鼠的尿路上皮肿瘤发生。
Molecules. 2023 Feb 9;28(4):1666. doi: 10.3390/molecules28041666.
7
In vitro inhibition of carboxylesterase 1 by Kava (Piper methysticum) Kavalactones.胡椒科卡瓦胡椒(Piper methysticum)中的卡瓦酮对羧酸酯酶 1 的体外抑制作用。
Chem Biol Interact. 2022 Apr 25;357:109883. doi: 10.1016/j.cbi.2022.109883. Epub 2022 Mar 9.
8
In vivo Structure-Activity Relationship of Dihydromethysticin in Reducing Nicotine-Derived Nitrosamine Ketone (NNK)-Induced Lung DNA Damage against Lung Carcinogenesis in A/J Mice.体内二氢血根碱降低烟碱衍生亚硝胺酮(NNK)诱导的肺 DNA 损伤对 A/J 小鼠肺癌发生的构效关系。
ChemMedChem. 2022 Apr 5;17(7):e202100727. doi: 10.1002/cmdc.202100727. Epub 2022 Mar 4.
9
Biological Activity, Hepatotoxicity, and Structure-Activity Relationship of Kavalactones and Flavokavins, the Two Main Bioactive Components in Kava ().卡瓦(Kava)中两种主要生物活性成分——卡瓦内酯和黄酮卡瓦素的生物活性、肝毒性及构效关系
Evid Based Complement Alternat Med. 2021 Aug 20;2021:6851798. doi: 10.1155/2021/6851798. eCollection 2021.
10
Kava as a Clinical Nutrient: Promises and Challenges.卡瓦作为一种临床营养素:前景与挑战。
Nutrients. 2020 Oct 5;12(10):3044. doi: 10.3390/nu12103044.