Gorska-Ciebiada Malgorzata, Masierek Malgorzata, Ciebiada Maciej
Department of Propaedeutics of Lifestyle Diseases, Medical University of Lodz, Poland.
Bioton S.A., ul. Starościńska 5, 02-516 Warsaw, Poland.
J Clin Transl Endocrinol. 2020 Feb 4;19:100217. doi: 10.1016/j.jcte.2020.100217. eCollection 2020 Mar.
The aim of this study was to elucidate injection techniques, treatment satisfaction and glycemic control after education among patients with type 2 diabetes.
4513 insulin-treated diabetic patients enrolled in the observational study EGIDA II (Education and GensuPen In Diabetology II) filled out the questionnaire which focused on key insulin injection parameters, pain sensation scale and satisfaction of the treatment form before (visit 1) and after 3 months treatment with insulin injection (visit 2). The education was performed by trained healthcare professionals. To assess the utility and comfort during using new automatic injection system (GensuPen) we separated 2 groups: A - treated with GensuPen and B - treated with other pens.
The education resulted in increased number of patients who properly remix cloudy insulin; inject insulin into skin; change every time the injection site; use the pen needle only once; prepare a pen for injection and store insulin. We noticed significant decrease in BMI and sensation of pain in both groups. Our study revealed that patients' satisfaction with the treatment increased with each of the 5 items (type of the treatment, mood, physical activity, vital energy, a sense of control over the disease) using a 5-point scale, with greater increase in group A. The utility and comfort (weight, thickness, easiness in remove pen cap, cleaning, twisting, keeping in hand the pen, dial the dose, readable signaling of injected dose) during using the GensuPen significantly increased in group A. Finally the mean glucose level in self-control diary was significantly lower after 3 months of the treatment in both groups, however the difference between visit 1 and 2 was greater in group A.
The study showed that proper selection of pen and professional education can result in the improvement of insulin injection technique, higher patients' satisfaction and better glycemic control.
本研究旨在阐明2型糖尿病患者接受教育后的注射技术、治疗满意度和血糖控制情况。
4513名参与观察性研究EGIDA II（糖尿病教育与GensuPen II）的胰岛素治疗糖尿病患者在胰岛素注射治疗前（第1次就诊）和治疗3个月后（第2次就诊）填写了问卷，问卷聚焦于关键胰岛素注射参数、疼痛感觉量表和治疗形式满意度。教育由经过培训的医疗专业人员进行。为评估使用新型自动注射系统（GensuPen）时的实用性和舒适度，我们将患者分为两组：A组——使用GensuPen治疗；B组——使用其他笔治疗。
教育使正确混合中效胰岛素、将胰岛素注射到皮下、每次更换注射部位、仅使用一次笔用针头、准备笔用于注射以及储存胰岛素的患者数量增加。我们注意到两组患者的体重指数和疼痛感觉均显著下降。我们的研究表明，患者对治疗的满意度在使用5分制的5个项目（治疗类型、情绪、身体活动、活力、对疾病的控制感）中均有所提高，A组提高幅度更大。A组使用GensuPen期间的实用性和舒适度（重量、粗细、取下笔帽的难易程度、清洁、扭转、握笔手感、调节剂量、注射剂量可读信号）显著提高。最后，两组患者在治疗3个月后自我控制日记中的平均血糖水平均显著降低，但A组第1次和第2次就诊之间的差异更大。
该研究表明，正确选择笔具和专业教育可改善胰岛素注射技术、提高患者满意度并更好地控制血糖。
